Date published: 2025-10-14

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4-Phenyl-3-buten-2-one (CAS 122-57-6)

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CAS Number:
122-57-6
Molecular Weight:
146.19
Molecular Formula:
C10H10O
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Phenyl-3-buten-2-one is characterized by its clear to pale yellow appearance and may have a distinctive, somewhat sweet odor. The presence of both a ketone functional group and a phenyl ring in its structure makes 4-Phenyl-3-buten-2-one a versatile compound in organic synthesis. It can participate in various chemical reactions, including condensations, additions, and cyclization reactions, making it a valuable intermediate in the synthesis of more complex organic molecules. In the realm of synthetic organic chemistry, 4-Phenyl-3-buten-2-one is often explored for its potential in constructing aromatic compounds, polymers, and other functional materials. Its ability to undergo reactions typical of ketones and alkenes allows chemists to manipulate the molecule into a wide array of derivatives with specific properties or activities.


4-Phenyl-3-buten-2-one (CAS 122-57-6) References

  1. Structure-activity relationship in potentially anti-tumor promoting benzalacetone derivatives, as assayed by the epstein-barr virus early antigen activation.  |  Motohashi, N., et al. 2000. Mutat Res. 464: 247-54. PMID: 10648911
  2. Structure-antimutagenic activity relationships of benzalacetone derivatives against UV-induced mutagenesis in E. coli WP2uvrA and gamma-induced mutagenesis in Salmonella typhimurium TA2638.  |  Motohashi, N., et al. 2001. Mutat Res. 474: 113-20. PMID: 11239968
  3. Role of 4-phenyl-3-buten-2-one in boar taint: identification of new compounds related to sensorial descriptors in pig fat.  |  Rius Solé, MA. and García Regueiro, JA. 2001. J Agric Food Chem. 49: 5303-9. PMID: 11714320
  4. Free energy profile and microkinetic modeling of base-catalyzed conjugate addition reaction of nitroalkanes to α,β-unsaturated ketones in polar and apolar solvents.  |  Rufino, VC., et al. 2018. J Mol Model. 24: 152. PMID: 29876745
  5. DABCO-based chiral ionic liquids as recoverable and reusable organocatalyst for asymmetric Diels-Alder reaction.  |  Aalam, MJ., et al. 2022. Chirality. 34: 134-146. PMID: 34762344
  6. Mannich bases of 4-phenyl-3-buten-2-one: a new class of antiherpes agent.  |  Edwards, ML., et al. 1983. J Med Chem. 26: 431-6. PMID: 6827562

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Phenyl-3-buten-2-one, 250 mg

sc-206934
250 mg
$337.00