Molecular structure of Protopanaxadiol, CAS Number: 7755-01-3
Protopanaxadiol (CAS 7755-01-3)
Alternate Names:
(20R)-protopanaxadiol
Application:
Protopanaxadiol is a tetracyclic ginsenoside compound
CAS Number:
7755-01-3
Molecular Weight:
460.73
Molecular Formula:
C30H52O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Protopanaxadiol is a ginseng saponin that enhances axonal and dendritic formation activity. Shown to have characteristic effects on the proliferation of human leukemia cells in vitro.
Protopanaxadiol (CAS 7755-01-3) References
- Structure-function relationship exists for ginsenosides in reducing cell proliferation and inducing apoptosis in the human leukemia (THP-1) cell line. | Popovich, DG. and Kitts, DD. 2002. Arch Biochem Biophys. 406: 1-8. PMID: 12234484
- Axonal and dendritic extension by protopanaxadiol-type saponins from ginseng drugs in SK-N-SH cells. | Tohda, C., et al. 2002. Jpn J Pharmacol. 90: 254-62. PMID: 12499580
- Protopanaxadiol inhibits epithelial-mesenchymal transition of hepatocellular carcinoma by targeting STAT3 pathway. | Yang, L., et al. 2019. Cell Death Dis. 10: 630. PMID: 31431619
- Protopanaxadiol alleviates neuropathic pain by spinal microglial dynorphin A expression following glucocorticoid receptor activation. | Shoaib, RM., et al. 2021. Br J Pharmacol. 178: 2976-2997. PMID: 33786848
- Protopanaxadiol improves endometriosis associated infertility and miscarriage in sex hormones receptors-dependent and independent manners. | Lai, ZZ., et al. 2021. Int J Biol Sci. 17: 1878-1894. PMID: 34131393
- Protopanaxadiol and Protopanaxatriol Ginsenosides Can Protect Against Aconitine-induced Injury in H9c2 Cells by Maintaining Calcium Homeostasis and Activating the AKT Pathway. | Zhao, Y., et al. 2021. J Cardiovasc Pharmacol. 78: e690-e702. PMID: 34369901
- Ginsenosides in Panax genus and their biosynthesis. | Hou, M., et al. 2021. Acta Pharm Sin B. 11: 1813-1834. PMID: 34386322
- Ginsenoside protopanaxadiol protects adult retinal pigment epithelial-19 cells from chloroquine by modulating autophagy and apoptosis. | Lee, H., et al. 2022. PLoS One. 17: e0274763. PMID: 36454967
- Protopanaxadiol-Enriched Rice Extracts Suppressed Oxidative and Melanogenic Activities in Melan-a Cells. | Monmai, C., et al. 2023. Antioxidants (Basel). 12: PMID: 36671028
- Recent Advances in Yeast Recombinant Biosynthesis of the Triterpenoid Protopanaxadiol and Glycosylated Derivatives Thereof. | Qiu, S. and Blank, LM. 2023. J Agric Food Chem. 71: 2197-2210. PMID: 36696911
- Protopanaxadiol manipulates gut microbiota to promote bone marrow hematopoiesis and enhance immunity in cyclophosphamide-induced immunosuppression mice. | Cao, Y., et al. 2023. MedComm (2020). 4: e222. PMID: 36845073
- Protopanaxadiol ameliorates palmitate-induced lipotoxicity and pancreatic β-cell dysfunction in INS-1 cells. | Lee, D., et al. 2023. J Ginseng Res. 47: 572-582. PMID: 37397416
- Protopanaxadiol-Enriched Rice Exerted Antiadipogenic Activity during 3T3-L1 Differentiation and Anti-Inflammatory Activity in 3T3-L1 Adipocytes. | Monmai, C., et al. 2023. Pharmaceutics. 15: PMID: 37631337
Inhibitor of:
GD3 Synthase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Protopanaxadiol, 5 mg | sc-205819 | 5 mg | $230.00 | |||
Protopanaxadiol, 10 mg | sc-205819A | 10 mg | $295.00 |