Date published: 2025-11-20

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Notoginsenoside R1 (CAS 80418-24-2)

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Application:
Notoginsenoside R1 is a biochemical for proteomics research
CAS Number:
80418-24-2
Purity:
≥98%
Molecular Weight:
933.13
Molecular Formula:
C47H80O18
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Notoginsenoside R1 is an active ingredient isolated from Panax notoginseng that induces tissue-type plasminogen activator synthesis in cultured human umbilical vein endothelial cells.


Notoginsenoside R1 (CAS 80418-24-2) References

  1. Notoginsenoside R1 Ameliorates Diabetic Retinopathy through PINK1-Dependent Activation of Mitophagy.  |  Zhou, P., et al. 2019. Cells. 8: PMID: 30832367
  2. Focus on Notoginsenoside R1 in Metabolism and Prevention Against Human Diseases.  |  Liu, H., et al. 2020. Drug Des Devel Ther. 14: 551-565. PMID: 32103897
  3. Notoginsenoside R1 attenuates sevoflurane-induced neurotoxicity.  |  Zhang, Y., et al. 2020. Transl Neurosci. 11: 215-226. PMID: 33335762
  4. Notoginsenoside R1-loaded mesoporous silica nanoparticles targeting the site of injury through inflammatory cells improves heart repair after myocardial infarction.  |  Li, H., et al. 2022. Redox Biol. 54: 102384. PMID: 35777198
  5. Pharmacological properties and mechanisms of Notoginsenoside R1 in ischemia-reperfusion injury.  |  Zhu, T. and Wan, Q. 2023. Chin J Traumatol. 26: 20-26. PMID: 35922249
  6. Notoginsenoside R1 protects against myocardial ischemia/reperfusion injury in mice via suppressing TAK1-JNK/p38 signaling.  |  Zeng, JJ., et al. 2023. Acta Pharmacol Sin. 44: 1366-1379. PMID: 36721009
  7. Notoginsenoside R1 inhibits hepatitis B virus replication by modulating SIRT1 activity.  |  Zhang, W., et al. 2023. Acta Virol. 67: 51-58. PMID: 36950885
  8. Notoginsenoside R1 protects against hypobaric hypoxia-induced high-altitude pulmonary edema by inhibiting apoptosis via ERK1/2-P90rsk-BAD ignaling pathway.  |  Pei, C., et al. 2023. Eur J Pharmacol. 959: 176065. PMID: 37775017
  9. Notoginsenoside R1 alleviates cerebral ischemia/reperfusion injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway through microbiota-gut-brain axis.  |  Zhang, S., et al. 2024. Phytomedicine. 128: 155530. PMID: 38493723
  10. Effect of notoginsenoside R1 on the synthesis of tissue-type plasminogen activator and plasminogen activator inhibitor-1 in cultured human umbilical vein endothelial cells.  |  Zhang, W., et al. 1994. Arterioscler Thromb. 14: 1040-6. PMID: 8018658

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Notoginsenoside R1, 5 mg

sc-205772
5 mg
$141.00

Notoginsenoside R1, 10 mg

sc-205772A
10 mg
$204.00