Date published: 2025-11-20

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Flavanone (CAS 487-26-3)

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Alternate Names:
2,3-Dihydroflavone; 2-Phenylchromanone
Application:
Flavanone is a natural plant flavonoid
CAS Number:
487-26-3
Purity:
≥98%
Molecular Weight:
224.25
Molecular Formula:
C15H12O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Flavanone is a compound that functions as a chemical precursor in various experimental applications. It serves as a key intermediate in the biosynthesis of flavonoids, playing the role in the formation of diverse secondary metabolites. Through a series of enzymatic reactions, flavanone undergoes structural modifications to yield a wide array of flavonoid compounds, contributing to diversity of plant-derived substances. At the molecular level, flavanone interacts with specific enzymes and undergoes catalytic transformations, leading to the production of various downstream metabolites.


Flavanone (CAS 487-26-3) References

  1. Comparative analysis of the effects of flavonoids on proliferation, cytotoxicity, and apoptosis in human colon cancer cell lines.  |  Kuntz, S., et al. 1999. Eur J Nutr. 38: 133-42. PMID: 10443335
  2. A flavanone and a dihydrodibenzoxepin from Bauhinia variegata.  |  Reddy, MV., et al. 2003. Phytochemistry. 64: 879-82. PMID: 14559285
  3. Flavanone exhibits PPARgamma ligand activity and enhances differentiation of 3T3-L1 adipocytes.  |  Saito, T., et al. 2009. Biochem Biophys Res Commun. 380: 281-5. PMID: 19167359
  4. Flavanone and diphenylpropane glycosides and glycosidic acyl esters from Viscum articulatum.  |  Kuo, YJ., et al. 2010. J Nat Prod. 73: 109-14. PMID: 20121165
  5. Flavanone and isoflavone glucosylation by non-Leloir glycosyltransferases.  |  Overwin, H., et al. 2016. J Biotechnol. 233: 121-8. PMID: 27374405
  6. Structure-activity relationship of flavanone. Anti-degranulation activity of 7-O-substituted hesperetin.  |  Noshita, T., et al. 2017. Nat Prod Res. 31: 2137-2142. PMID: 28105859
  7. Effect of Hesperidin on Cardiovascular Disease Risk Factors: The Role of Intestinal Microbiota on Hesperidin Bioavailability.  |  Mas-Capdevila, A., et al. 2020. Nutrients. 12: PMID: 32443766
  8. Naringenin, a flavanone with antiviral and anti-inflammatory effects: A promising treatment strategy against COVID-19.  |  Tutunchi, H., et al. 2020. Phytother Res. 34: 3137-3147. PMID: 32613637
  9. A new flavanone derivative from the rhizomes of Boesenbergia pandurata.  |  Nguyen, MTT., et al. 2022. Nat Prod Res. 36: 1959-1965. PMID: 33138655
  10. Deuterium effects on the vibrational circular dichroism spectra of flavanone.  |  Muñoz, MA. and Joseph-Nathan, P. 2021. Chirality. 33: 81-92. PMID: 33242919
  11. (±)-Involucrasins A and B, two pairs of flavanone enantiomers from Shuteria involucrata and their inhibitory effects on the proliferation of various cancer cell lines.  |  Liu, L., et al. 2022. J Asian Nat Prod Res. 24: 641-647. PMID: 34304657
  12. Molecular Characterisation of Flavanone O-methylation in Eucalyptus.  |  Somaletha Chandran, K., et al. 2022. Int J Mol Sci. 23: PMID: 35328610
  13. Synthesis and Investigation of Flavanone Derivatives as Potential New Anti-Inflammatory Agents.  |  Sinyeue, C., et al. 2022. Molecules. 27: PMID: 35335145
  14. Citrus flavanone metabolites significantly modulate global proteomic profile in pancreatic β-cells under high-glucose-induced metabolic stress.  |  Fraga, LN., et al. 2023. Biochim Biophys Acta Proteins Proteom. 1871: 140898. PMID: 36731758
  15. Naringenin: A flavanone with anti-inflammatory and anti-infective properties.  |  Cai, J., et al. 2023. Biomed Pharmacother. 164: 114990. PMID: 37315435

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Flavanone, 10 g

sc-205693
10 g
$45.00

Flavanone, 25 g

sc-205693A
25 g
$109.00