Molecular structure of Cafestol palmitate, CAS Number: 81760-46-5
Cafestol palmitate (CAS 81760-46-5)
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Application:
Cafestol palmitate is a naturally occuring ester
CAS Number:
81760-46-5
Purity:
≥97%
Molecular Weight:
554.43
Molecular Formula:
C36H58O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Cafestol palmitate is present in coffee beans and is a diterpene ester, recognized as one of the components contributing to the unique lipid fraction in coffee. It is used as a reference material to calibrate analytical instruments like gas chromatography-mass spectrometry (GC-MS). Cafestol palmitate has also been the subject of investigations regarding its interactions with proteins within the body. Specifically, it has been observed to bind to and activate proteins such as the peroxisome proliferator-activated receptor gamma (PPARγ), which plays a role in metabolic regulation and cellular development.
Cafestol palmitate (CAS 81760-46-5) References
- The coffee diterpene cafestol increases plasma triacylglycerol by increasing the production rate of large VLDL apolipoprotein B in healthy normolipidemic subjects. | de Roos, B., et al. 2001. Am J Clin Nutr. 73: 45-52. PMID: 11124749
- Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepatic N-acetyltransferase and glutathione S-transferase activities. | Huber, WW., et al. 2004. Environ Mol Mutagen. 44: 265-76. PMID: 15468054
- Coffee diterpenes prevent the genotoxic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and N-nitrosodimethylamine in a human derived liver cell line (HepG2). | Majer, BJ., et al. 2005. Food Chem Toxicol. 43: 433-41. PMID: 15680679
- Kahweol and cafestol: inhibitors of hamster buccal pouch carcinogenesis. | Miller, EG., et al. 1991. Nutr Cancer. 15: 41-6. PMID: 2017397
- Liquid chromatography with diode array detection combined with spectral deconvolution for the analysis of some diterpene esters in Arabica coffee brew. | Erny, GL., et al. 2015. J Sep Sci. 38: 612-20. PMID: 25521818
- New approaches on the analyses of thermolabile coffee diterpenes by gas chromatography and its relationship with cup quality. | Novaes, FJ., et al. 2015. Talanta. 139: 159-66. PMID: 25882422
- Effects of inducers of drug metabolism on basic hepatic forms of mouse glutathione transferase. | Di Simplicio, P., et al. 1989. Biochem J. 263: 679-85. PMID: 2597126
- Variability of some diterpene esters in coffee beverages as influenced by brewing procedures. | Moeenfard, M., et al. 2016. J Food Sci Technol. 53: 3916-3927. PMID: 28035147
- Lipase-catalysed esters synthesis of cafestol and kahweol. | Novaes, FJM., et al. 2018. Food Chem. 259: 226-233. PMID: 29680048
- Inhibition Mechanisms of Hepatitis C Virus Infection by Caffeic Acid and Tannic Acid. | Shirasago, Y., et al. 2019. Biol Pharm Bull. 42: 770-777. PMID: 31061319
- Interaction of the Coffee Diterpenes Cafestol and 16-O-Methyl-Cafestol Palmitates with Serum Albumins. | Berti, F., et al. 2020. Int J Mol Sci. 21: PMID: 32155814
- Effects of derivatives of kahweol and cafestol on the activity of glutathione S-transferase in mice. | Lam, LK., et al. 1987. J Med Chem. 30: 1399-403. PMID: 3612687
- Diterpenes of Coffea seeds show antifungal and anti-insect activities and are transferred from the endosperm to the seedling after germination. | Antoine, G., et al. 2023. Plant Physiol Biochem. 194: 627-637. PMID: 36535102
- Isolation and identification of kahweol palmitate and cafestol palmitate as active constituents of green coffee beans that enhance glutathione S-transferase activity in the mouse. | Lam, LK., et al. 1982. Cancer Res. 42: 1193-8. PMID: 7059995
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cafestol palmitate, 50 mg | sc-205613 | 50 mg | $414.00 | |||
Cafestol palmitate, 100 mg | sc-205613A | 100 mg | $516.00 |