Molecular structure of Traumatic Acid, CAS Number: 6402-36-4
Traumatic Acid (CAS 6402-36-4)
Alternate Names:
trans-2-Dodecenedioic Acid
Application:
Traumatic Acid is a product of the hydroperoxide lyase pathway in plants
CAS Number:
6402-36-4
Molecular Weight:
228.30
Molecular Formula:
C12H20O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Traumatic Acid is a product of the hydroperoxide lyase pathway in plants. Potential as a wound healing agent that stimulates cell division near a wound site to form a protective callus. it is believed that Traumatic acid may act by modulating the activity of proteins involved in inflammation, such as NF-κB and COX-2. In addition, Traumatic acid may reduce the production of ROS and protect cells from oxidative damage.
Traumatic Acid (CAS 6402-36-4) References
- Volatile Products of the Lipoxygenase Pathway Evolved from Phaseolus vulgaris (L.) Leaves Inoculated with Pseudomonas syringae pv phaseolicola. | Croft, K., et al. 1993. Plant Physiol. 101: 13-24. PMID: 12231661
- Suberization: inhibition by washing and stimulation by abscisic Acid in potato disks and tissue culture. | Soliday, CL., et al. 1978. Plant Physiol. 61: 170-4. PMID: 16660254
- Identification of Traumatin, a Wound Hormone, as 12-Oxo-trans-10-dodecenoic Acid. | Zimmerman, DC. and Coudron, CA. 1979. Plant Physiol. 63: 536-41. PMID: 16660762
- C12 derivatives of the hydroperoxide lyase pathway are produced by product recycling through lipoxygenase-2 in Nicotiana attenuata leaves. | Kallenbach, M., et al. 2011. New Phytol. 191: 1054-1068. PMID: 21615741
- [Study on intervention effect of Jieduquyuziyin prescription systemic lupus erythematosus by HPLC-Q-TOF/MS]. | Hu, JB., et al. 2013. Zhongguo Zhong Yao Za Zhi. 38: 3747-52. PMID: 24494566
- Rapid resolution liquid chromatography coupled with quadrupole time-of-flight mass spectrometry-based metabolomics approach to study the effects of jieduquyuziyin prescription on systemic lupus erythematosus. | Ding, X., et al. 2014. PLoS One. 9: e88223. PMID: 24505438
- Traumatic Acid Reduces Oxidative Stress and Enhances Collagen Biosynthesis in Cultured Human Skin Fibroblasts. | Jabłońska-Trypuć, A., et al. 2016. Lipids. 51: 1021-35. PMID: 27423205
- Toxicological Effects of Traumatic Acid and Selected Herbicides on Human Breast Cancer Cells: In Vitro Cytotoxicity Assessment of Analyzed Compounds. | Jabłońska-Trypuć, A., et al. 2019. Molecules. 24: PMID: 31052542
- Traumatic acid toxicity mechanisms in human breast cancer MCF-7 cells. | Jabłońska-Trypuć, A., et al. 2019. Regul Toxicol Pharmacol. 106: 137-146. PMID: 31055047
- Identification of traumatic acid as a potential plasma biomarker for sarcopenia using a metabolomics-based approach. | Tsai, JS., et al. 2022. J Cachexia Sarcopenia Muscle. 13: 276-286. PMID: 34939349
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Traumatic Acid, 500 mg | sc-205532 | 500 mg | $108.00 | |||
Traumatic Acid, 1 g | sc-205532A | 1 g | $272.00 | |||
Traumatic Acid, 5 g | sc-205532B | 5 g | $863.00 | |||
Traumatic Acid, 10 g | sc-205532C | 10 g | $1710.00 |