Date published: 2025-10-19

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Palmitic Acid methyl ester (CAS 112-39-0)

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Alternate Names:
Methyl Palmitate
Application:
Palmitic Acid methyl ester is a saturated fatty acid ester
CAS Number:
112-39-0
Molecular Weight:
270.45
Molecular Formula:
C17H34O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Palmitic Acid methyl ester is a 17 carbon saturated fatty acid ester. This agent has also been reported to cause autolysis of membranous structures, especially mitochondria. Studies on rat superior cervical ganglion (SCG) suggest that Palmitic Acid methyl ester is released from SCG and induces significant aortic dilation. Furthermore, this compound displays the ability to inhibit phagocytic activity and NO production of certain cells. Additionally, Palmitic Acid methyl ester appears to reduce levels of TNFalpha, PGE2, and IL-10 without affecting ATP levels. Palmitic Acid methyl ester is an inhibitor of NF kappa B. It presents as a white, waxy solid with solubility in organic solvents and a faint, recognizable scent. This compound occurs naturally in certain plant and animal fats and oils, and it is employed as a food additive and preservative. In scientific and medical research, Palmitic Acid methyl ester plays a significant role. It aids in the examination of fatty acid structure and properties, as well as the assessment of how fatty acid esters impact enzymes and other proteins. The compound also contributes to the exploration of lipid metabolism and its association with diseases.


Palmitic Acid methyl ester (CAS 112-39-0) References

  1. Fatty acid protection from palmitic acid-induced apoptosis is lost following PI3-kinase inhibition.  |  Beeharry, N., et al. 2004. Apoptosis. 9: 599-607. PMID: 15314288
  2. Methyl palmitate: inhibitor of phagocytosis in primary rat Kupffer cells.  |  Cai, P., et al. 2005. Toxicology. 210: 197-204. PMID: 15840433
  3. Methyl palmitate inhibits lipopolysaccharide-stimulated phagocytic activity of rat peritoneal macrophages.  |  Sarkar, S., et al. 2006. J Biochem Mol Toxicol. 20: 302-8. PMID: 17163484
  4. Endogenous methyl palmitate modulates nicotinic receptor-mediated transmission in the superior cervical ganglion.  |  Lin, HW., et al. 2008. Proc Natl Acad Sci U S A. 105: 19526-31. PMID: 19057014
  5. Assessment of the contact toxicity of methyl palmitate on Tetranychus viennensis (Acari: Tetranychidae).  |  Wang, YN., et al. 2010. J Econ Entomol. 103: 1372-7. PMID: 20857750
  6. An evidence of C16 fatty acid methyl esters extracted from microalga for effective antimicrobial and antioxidant property.  |  Davoodbasha, M., et al. 2018. Microb Pathog. 115: 233-238. PMID: 29277474
  7. Palmitic Acid Methyl Ester and Its Relation to Control of Tone of Human Visceral Arteries and Rat Aortas by Perivascular Adipose Tissue.  |  Wang, N., et al. 2018. Front Physiol. 9: 583. PMID: 29875688
  8. Palmitic acid methyl ester is a novel neuroprotective agent against cardiac arrest.  |  Lee, RH., et al. 2019. Prostaglandins Leukot Essent Fatty Acids. 147: 6-14. PMID: 30514597
  9. Palmitic Acid Methyl Ester Induces G2/M Arrest in Human Bone Marrow-Derived Mesenchymal Stem Cells via the p53/p21 Pathway.  |  Lin, JH., et al. 2019. Stem Cells Int. 2019: 7606238. PMID: 31885624
  10. COMT-Catalyzed Palmitic Acid Methyl Ester Biosynthesis in Perivascular Adipose Tissue and its Potential Role Against Hypertension.  |  Liu, CH., et al. 2020. J Pharmacol Exp Ther. 373: 175-183. PMID: 32071104
  11. Palmitic acid methyl ester inhibits cardiac arrest-induced neuroinflammation and mitochondrial dysfunction.  |  Wu, CY., et al. 2021. Prostaglandins Leukot Essent Fatty Acids. 165: 102227. PMID: 33445063
  12. Palmitic acid methyl ester induces cardiac hypertrophy through activating the GPR receptor-mediated changes of intracellular calcium concentrations and mitochondrial functions.  |  Lien, CF., et al. 2023. J Cell Physiol. 238: 242-256. PMID: 36538623
  13. P-selectin is acylated with palmitic acid and stearic acid at cysteine 766 through a thioester linkage.  |  Fujimoto, T., et al. 1993. J Biol Chem. 268: 11394-400. PMID: 7684381

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Palmitic Acid methyl ester, 1 g

sc-204829
1 g
$15.00

Palmitic Acid methyl ester, 5 g

sc-204829A
5 g
$58.00

Palmitic Acid methyl ester, 10 g

sc-204829B
10 g
$112.00

Palmitic Acid methyl ester, 25 g

sc-204829C
25 g
$230.00