Molecular structure of Kahweol palmitate, CAS Number: 81760-45-4
Kahweol palmitate (CAS 81760-45-4)
Application:
Kahweol palmitate is a naturally occuring ester of green coffee beans
CAS Number:
81760-45-4
Purity:
≥97%
Molecular Weight:
552.84
Molecular Formula:
C36H56O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Kahweol palmitate is a naturally occurring ester present in green coffee beans that inhibits mammary tumor formation. The compound demonstrates a diverse range of biological activities, encompassing the inhibition of RANKL-induced osteoclast formation, induction of cell cycle arrest and apoptosis in oral squamous cell carcinoma cells. It also prevents DNA adduct formation caused by aflatoxin B1. Kahweol palmitate suppresses DNA damage and oxidative stress induced by H2O2.
Kahweol palmitate (CAS 81760-45-4) References
- The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes. | McMahon, M., et al. 2001. Cancer Res. 61: 3299-307. PMID: 11309284
- Inhibition of carcinogenesis by minor dietary constituents. | Wattenberg, LW. 1992. Cancer Res. 52: 2085s-2091s. PMID: 1544145
- Kahweol and cafestol: inhibitors of hamster buccal pouch carcinogenesis. | Miller, EG., et al. 1991. Nutr Cancer. 15: 41-6. PMID: 2017397
- The effect of citrus limonoids on hamster buccal pouch carcinogenesis. | Miller, EG., et al. 1989. Carcinogenesis. 10: 1535-7. PMID: 2502323
- New approaches on the analyses of thermolabile coffee diterpenes by gas chromatography and its relationship with cup quality. | Novaes, FJ., et al. 2015. Talanta. 139: 159-66. PMID: 25882422
- Anti-Angiogenic Properties of Cafestol and Kahweol Palmitate Diterpene Esters. | Moeenfard, M., et al. 2016. J Cell Biochem. 117: 2748-2756. PMID: 27129115
- Variability of some diterpene esters in coffee beverages as influenced by brewing procedures. | Moeenfard, M., et al. 2016. J Food Sci Technol. 53: 3916-3927. PMID: 28035147
- Lipase-catalysed esters synthesis of cafestol and kahweol. | Novaes, FJM., et al. 2018. Food Chem. 259: 226-233. PMID: 29680048
- Effects of derivatives of kahweol and cafestol on the activity of glutathione S-transferase in mice. | Lam, LK., et al. 1987. J Med Chem. 30: 1399-403. PMID: 3612687
- Inhibition of carcinogenesis by some minor dietary constituents. | Wattenberg, LW., et al. 1985. Princess Takamatsu Symp. 16: 193-203. PMID: 3916195
- Inhibition of neoplasia by minor dietary constituents. | Wattenberg, LW. 1983. Cancer Res. 43: 2448s-2453s. PMID: 6403236
- Isolation and identification of kahweol palmitate and cafestol palmitate as active constituents of green coffee beans that enhance glutathione S-transferase activity in the mouse. | Lam, LK., et al. 1982. Cancer Res. 42: 1193-8. PMID: 7059995
- Variations in Diterpenes-Cafestol and Kahweol Content in Beans of Robusta Coffee Grown at Different Altitudes | , et al. (2016). Proceedings of the National Academy of Sciences, India Section B: Biological Sciences. volume 86,: pages 291–297.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Kahweol palmitate, 10 mg | sc-204779 | 10 mg | $408.00 | |||
Kahweol palmitate, 25 mg | sc-204779A | 25 mg | $816.00 | |||
Kahweol palmitate, 500 mg | sc-204779B | 500 mg | $5100.00 |