Esculin (CAS 531-75-9)
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Esculin functions as a fluorescent dye. It is used to detect the presence of metal ions, particularly iron, in biological samples. Esculin interacts with metal ions at the molecular level, forming complexes that emit fluorescence when exposed to specific wavelengths of light. This property allows visualization and quantification the amount of metal ions present in experimental samples. Esculin′s mechanism of action involves chelation, where it binds to metal ions and forms stable complexes, leading to the emission of fluorescence. This enables to study the distribution and concentration of metal ions within biological systems, providing insights into various biochemical processes. Esculin hydrate plays a role in facilitating the detection and analysis of metal ions in experimental, contributing to a better understanding of biological systems and processes.
Esculin (CAS 531-75-9) References
- Protective effect of esculin on streptozotocin-induced diabetic renal damage in mice. | Kang, KS., et al. 2014. J Agric Food Chem. 62: 2069-76. PMID: 24484395
- Esculin and its oligomer fractions inhibit adhesion and migration of U87 glioblastoma cells and in vitro angiogenesis. | Mokdad-Bzeouich, I., et al. 2016. Tumour Biol. 37: 3657-64. PMID: 26459313
- Gastroprotective effect of esculin on ethanol-induced gastric lesion in mice. | Li, W., et al. 2017. Fundam Clin Pharmacol. 31: 174-184. PMID: 27873354
- Esculin prevents Lipopolysaccharide/D-Galactosamine-induced acute liver injury in mice. | Liu, A., et al. 2018. Microb Pathog. 125: 418-422. PMID: 30290266
- Esculin reduces P2X7 and reverses mitochondrial dysfunction in the renal cortex of diabetic rats. | Serralha, RS., et al. 2020. Life Sci. 254: 117787. PMID: 32417372
- [Esculin inhibits proliferation of triple negative breast cancer cells by down-regulating FBI-1]. | Mo, M., et al. 2020. Zhonghua Zhong Liu Za Zhi. 42: 629-634. PMID: 32867453
- Esculin and ferric citrate-incorporated sturgeon skin gelatine as an antioxidant film for food packaging to prevent Enterococcus faecalis contamination. | Tian, L., et al. 2020. Food Funct. 11: 9129-9143. PMID: 33026011
- Antiviral activity of esculin against white spot syndrome virus: A new starting point for prevention and control of white spot disease outbreaks in shrimp seedling culture. | Shan, LP., et al. 2022. J Fish Dis. 45: 59-68. PMID: 34536027
- Molecular interactions of esculin with bovine serum albumin and recognition of binding sites with spectroscopy and molecular docking. | Qureshi, MA., et al. 2023. J Biomol Struct Dyn. 41: 2630-2644. PMID: 35139760
- Co-treatment with Esculin and erythropoietin protects against renal ischemia-reperfusion injury via P2X7 receptor inhibition and PI3K/Akt activation. | El-Maadawy, WH., et al. 2022. Sci Rep. 12: 6239. PMID: 35422072
- The pharmacological and pharmacokinetic properties of esculin: A comprehensive review. | Li, CX., et al. 2022. Phytother Res. 36: 2434-2448. PMID: 35599456
- Esculin protects human blood cells from bioallethrin-induced toxicity: An ex vivo study. | Arif, A., et al. 2023. Pestic Biochem Physiol. 191: 105375. PMID: 36963944
- Esculin alleviates LPS-induced acute lung injury via inhibiting neutrophil recruitment and migration. | Ni, J., et al. 2023. Int Immunopharmacol. 119: 110177. PMID: 37068336
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Esculin, 5 g | sc-204744 | 5 g | $78.00 | |||
Esculin, 25 g | sc-204744A | 25 g | $256.00 |