Molecular structure of Erucin, CAS Number: 4430-36-8
Erucin (CAS 4430-36-8)
See product citations (22)
Alternate Names:
4-methylthiobutyl isothiocyanate; 1-isothiocyanato-4-(methylthio)-butane
Application:
Erucin is effecient biochemical for apoptosis induction and mitochondrial potiential dissipation
CAS Number:
4430-36-8
Purity:
≥98%
Molecular Weight:
161.29
Molecular Formula:
C6H11NS2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Erucin is a compound that acts as a non-competitive antagonist of the aryl hydrocarbon (Ah) receptor. Erucin, derived from glucoerucin found in arugula and other cruciferous vegetables, is an isothiocyanate. It has demonstrated antioxidant properties, inhibits cell proliferation in cancer cell lines, and induces apoptosis.
Erucin (CAS 4430-36-8) References
- Erucin, a new promising cancer chemopreventive agent from rocket salads, shows anti-proliferative activity on human lung carcinoma A549 cells. | Melchini, A., et al. 2009. Food Chem Toxicol. 47: 1430-6. PMID: 19328833
- Erucin exerts anti-inflammatory properties in murine macrophages and mouse skin: possible mediation through the inhibition of NFκB signaling. | Cho, HJ., et al. 2013. Int J Mol Sci. 14: 20564-77. PMID: 24132147
- Erucin, the major isothiocyanate in arugula (Eruca sativa), inhibits proliferation of MCF7 tumor cells by suppressing microtubule dynamics. | Azarenko, O., et al. 2014. PLoS One. 9: e100599. PMID: 24950293
- Bioprotective Efficacy of Erucin Against 7,12-Dimethylbenz(α)anthracene-Induced Microstructural Changes in Male Wistar Rats. | Mannan, R., et al. 2017. Turk Patoloji Derg. 33: 150-156. PMID: 28272652
- Anticancer properties of erucin, an H2 S-releasing isothiocyanate, on human pancreatic adenocarcinoma cells (AsPC-1). | Citi, V., et al. 2019. Phytother Res. 33: 845-855. PMID: 30632211
- Erucin exhibits vasorelaxing effects and antihypertensive activity by H2 S-releasing properties. | Martelli, A., et al. 2020. Br J Pharmacol. 177: 824-835. PMID: 30825379
- Erucin modulates digestive enzyme release via crustacean cardioactive peptide in the elm leaf beetle Xanthogaleruca luteola (Coleoptera: Chrysomelidae). | Mashhoor, MV., et al. 2021. J Insect Physiol. 130: 104196. PMID: 33545106
- The H2S-Donor Erucin Exhibits Protective Effects against Vascular Inflammation in Human Endothelial and Smooth Muscle Cells. | Martelli, A., et al. 2021. Antioxidants (Basel). 10: PMID: 34203803
- Erucin inhibits osteoclast formation via suppressing cell-cell fusion molecule DC-STAMP without influencing mineralization by osteoblasts. | Takagi, T., et al. 2022. BMC Res Notes. 15: 105. PMID: 35296341
- Frankincense oil-loaded nanoemulsion formulation of paclitaxel and erucin: A synergistic combination for ameliorating drug resistance in breast cancer: In vitro and in vivo study. | Kaur, H., et al. 2022. Front Pharmacol. 13: 1020602. PMID: 36330087
- The Dietary Isothiocyanate Erucin Reduces Kidney Cell Motility by Disturbing Tubulin Polymerization. | Guerreiro, Í., et al. 2023. Mol Nutr Food Res. 67: e2200581. PMID: 36415106
- Anti-Inflammatory Effect of the Natural H2S-Donor Erucin in Vascular Endothelium. | Ciccone, V., et al. 2022. Int J Mol Sci. 23: PMID: 36555238
- Antiproliferative and Proapoptotic Effects of Erucin, a Diet-Derived H2S Donor, on Human Melanoma Cells. | Maresca, DC., et al. 2022. Antioxidants (Basel). 12: PMID: 36670903
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Erucin, 25 mg | sc-204741 | 25 mg | $173.00 | |||
Erucin, 50 mg | sc-204741A | 50 mg | $297.00 |