Molecular structure of (+)-Catechin, CAS Number: 225937-10-0
(+)-Catechin (CAS 225937-10-0)
See product citations (2)
Alternate Names:
(+)-Catechin hydrate; (2R,3S)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol; D-(+)-Catechin
Application:
(+)-Catechin is an inhibitor of free radical-induced oxidation of isolated LDL
CAS Number:
225937-10-0
Purity:
>98%
Molecular Weight:
290.27
Molecular Formula:
C15H14O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(+)-Catechin is a polyphenolic flavonoid which has been isolated from a variety of natural sources including grape seeds, tea leaves and the wood and bark of trees such as acacia and mahogany. (+)-Catechin is a more potent antioxidant than ascorbate or alpha-tocopherol in certain in vitro assays of lipid peroxidation. (+)-Catechin inhibits the free radical-induced oxidation of isolated LDL by AAPH and has also been reported to act as an inhibitor of Cox-1 with an IC50 of about 80 muM. (+)-Catechin also has antitumor activity when tested in a two-stage mouse epidermal carcinoma model employing topical application.
(+)-Catechin (CAS 225937-10-0) References
- Cytologic and virologic studies of herpetic pneumonia. | Ishiguro, T., et al. 1978. J Am Med Womens Assoc (1972). 33: 124-8. PMID: 204673
- Ascorbate improves metabolic abnormalities in Wrn mutant mice but not the free radical scavenger catechin. | Lebel, M., et al. 2010. Ann N Y Acad Sci. 1197: 40-4. PMID: 20536831
- Catechin hydrate suppresses MCF-7 proliferation through TP53/Caspase-mediated apoptosis. | Alshatwi, AA. 2010. J Exp Clin Cancer Res. 29: 167. PMID: 21167021
- Catechin hydrate inhibits proliferation and mediates apoptosis of SiHa human cervical cancer cells. | Al-Hazzani, AA. and Alshatwi, AA. 2011. Food Chem Toxicol. 49: 3281-6. PMID: 21967781
- Effect of (+)-catechin hydrate on oxidative stress induced by high sucrose and high fat diet in male Wistar rats. | Mehra, P., et al. 2013. Indian J Exp Biol. 51: 823-7. PMID: 24266106
- Nephroprotective effect of catechin on gentamicin-induced experimental nephrotoxicity. | Sardana, A., et al. 2015. Clin Exp Nephrol. 19: 178-84. PMID: 24825545
- Delineating the anti-cytotoxic and anti-genotoxic potentials of catechin hydrate against cadmium toxicity in human peripheral blood lymphocytes. | Alshatwi, AA., et al. 2014. Environ Toxicol Pharmacol. 38: 653-62. PMID: 25218093
- Modulatory effects of catechin hydrate against genotoxicity, oxidative stress, inflammation and apoptosis induced by benzo(a)pyrene in mice. | Shahid, A., et al. 2016. Food Chem Toxicol. 92: 64-74. PMID: 27020533
- Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in vitro and episodic memory deficit in in vivo in Wistar rats. | Cheruku, SP., et al. 2018. Cytotechnology. 70: 245-259. PMID: 28900743
- Undesirable impact on structure and stability of insulin on addition of (+)-catechin hydrate with sugar. | Rani, A., et al. 2018. Arch Biochem Biophys. 646: 64-71. PMID: 29604256
- Effects of Blue-Light-Induced Free Radical Formation from Catechin Hydrate on the Inactivation of Acinetobacter baumannii, Including a Carbapenem-Resistant Strain. | Yang, MJ., et al. 2018. Molecules. 23: PMID: 29973539
- Quantification and Evaluations of Catechin Hydrate Polymeric Nanoparticles Used in Brain Targeting for the Treatment of Epilepsy. | Ahmad, N., et al. 2020. Pharmaceutics. 12: PMID: 32120778
- Assessment of preclinical effect of (+)-catechin hydrate on sexual function: An in silico and in vivo study. | Rai, A., et al. 2020. Andrologia. 52: e13737. PMID: 32613640
- Mechanically Resistant Poly(N-vinylcaprolactam) Microgels with Sacrificial Supramolecular Catechin Hydrogen Bonds. | Izak-Nau, E., et al. 2022. Adv Sci (Weinh). 9: e2104004. PMID: 35187862
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(+)-Catechin, 1 g | sc-204673 | 1 g | $57.00 | |||
(+)-Catechin, 5 g | sc-204673A | 5 g | $108.00 | |||
(+)-Catechin, 10 g | sc-204673B | 10 g | $186.00 | |||
(+)-Catechin, 25 g | sc-204673C | 25 g | $390.00 |