Molecular structure of Bromhexine Hydrochloride, CAS Number: 611-75-6
Bromhexine Hydrochloride (CAS 611-75-6)
Alternate Names:
2-Amino-3,5-dibromo-N-cyclohexyl-N-methylbenzylamine hydrochloride, N-(2-Amino-3,5-dibromobenzyl)-N-methylcyclohexylamine hydrochloride
Application:
Bromhexine Hydrochloride is a secretagogic and mucolytic agent
CAS Number:
611-75-6
Molecular Weight:
412.60
Molecular Formula:
C14H20Br2N2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Bromhexine Hydrochloride is a compound that functions as an expectorant in experiment. It acts by increasing the production of respiratory tract secretions, which helps to liquefy and facilitate the removal of mucus. At the molecular level, Bromhexine Hydrochloride works by stimulating the activity of serous cells in the mucous glands, leading to an increase in the volume and fluidity of the mucus. This mechanism of action aids in the clearance of mucus from the airways, making it easier to study the effects of various compounds on respiratory function. Bromhexine Hydrochloride modulates the rheological properties of mucus, which can be beneficial in experimental models aimed at understanding the pathophysiology.
Bromhexine Hydrochloride (CAS 611-75-6) References
- Solubilization of bromhexine hydrochloride in aqueous lecithin dispersions. Physicochemical characterization of interactions between drug and carrier. | Schubert, MA. and Müller-Goymann, CC. 2001. Pharmazie. 56: 734-7. PMID: 11593995
- Chemiluminescence determination of bromhexine hydrochloride with morin as chemiluminescent reagent. | Jiang, Q., et al. 2008. Luminescence. 23: 32-6. PMID: 18175361
- Cyclodextrins: Efficient biocompatible solubilizing excipients for bromhexine liquid and semi-solid drug delivery systems. | Stojanov, M., et al. 2012. Int J Pharm. 422: 349-55. PMID: 22027391
- Extractive determination of ephedrine hydrochloride and bromhexine hydrochloride in pure solutions, pharmaceutical dosage form and urine samples. | Abdel-Ghani, NT., et al. 2013. Spectrochim Acta A Mol Biomol Spectrosc. 111: 131-41. PMID: 23624039
- The effects of bromhexine hydrochloride and S-carboxymethyl-L-cysteine on guinea-pig uterine microflora. | Malhi, JS., et al. 1987. J Pharm Pharmacol. 39: 1025-8. PMID: 2894430
- Possible use of the mucolytic drug, bromhexine hydrochloride, as a prophylactic agent against SARS-CoV-2 infection based on its action on the Transmembrane Serine Protease 2. | Habtemariam, S., et al. 2020. Pharmacol Res. 157: 104853. PMID: 32360584
- Evaluating the efficacy and safety of bromhexine hydrochloride tablets in treating pediatric COVID-19: A protocol for meta-analysis and systematic review. | Wang, Y., et al. 2020. Medicine (Baltimore). 99: e22114. PMID: 32925756
- Development and Validation of Two Novel Chromatographic Methods: HPTLC and HPLC for Determination of Bromhexine Hydrochloride in Presence of Its Two Impurities. | Abdelwahab, NS., et al. 2021. J Chromatogr Sci. 59: 425-431. PMID: 33532822
- Simultaneous analysis of oxytetracycline hydrochloride, lidocaine, and bromhexine hydrochloride in the presence of many interfering excipients. | Gamal, M., et al. 2021. Arch Pharm (Weinheim). 354: e2100131. PMID: 34131945
- Facile approaches for determination of Bromhexine Hydrochloride and its active metabolite Ambroxol Hydrochloride using Eosin Y. | El-Sayed, A., et al. 2022. Ann Pharm Fr. 80: 687-696. PMID: 34968477
- Electrodeposition of Cobalt Oxides on Carbon Nanotubes for Sensitive Bromhexine Sensing. | Lisnund, S., et al. 2022. Molecules. 27: PMID: 35807327
- Pharmacokinetics of bromhexine in the dog. | Vandecasteele-Thienpont, LM., et al. 1980. Arzneimittelforschung. 30: 1643-5. PMID: 7192102
- Simultaneous determination of bromhexine hydrochloride and methyl and propyl p-hydroxybenzoate and determination of dextromethorphan hydrobromide in cough-cold syrup by high-performance liquid chromatography. | Rauha, JP., et al. 1996. J Pharm Biomed Anal. 15: 287-93. PMID: 8933431
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bromhexine Hydrochloride, 25 g | sc-204656 | 25 g | $47.00 | |||
Bromhexine Hydrochloride, 100 g | sc-204656A | 100 g | $220.00 |