Molecular structure of Baicalin, CAS Number: 21967-41-9
Baicalin (CAS 21967-41-9)
See product citations (4)
Application:
Baicalin is a flavonoid compound with antioxidant effects
CAS Number:
21967-41-9
Purity:
≥95%
Molecular Weight:
446.37
Molecular Formula:
C21H18O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Baicalin is a flavonoid compound with anti-inflammatory and anti-oxidant activity extracted from Scutellarua rivularis. HIV studies show that Baicalin inhibits HIV-1 replication by blocking the activity of the reverse transcriptase (HIV-1 RT). Baicalin has been suggested by Neural Stem cell studies to act as a strong inducer of neural differentiation by activating Erk1/2. Additionally, Baicalin was reported to inhibit the up-regulation of the connective tissue growth factor, and blocks the TLR2/4 signaling pathway. Baicalin is an inhibitor of PREP. Baicalin, a flavonoid compound derived from the root of Scutellaria baicalensis Georgi.
Baicalin (CAS 21967-41-9) References
- Comparison of metabolic pharmacokinetics of baicalin and baicalein in rats. | Lai, MY., et al. 2003. J Pharm Pharmacol. 55: 205-9. PMID: 12631413
- Stability of baicalin in biological fluids in vitro. | Xing, J., et al. 2005. J Pharm Biomed Anal. 39: 593-600. PMID: 15894449
- Absorption and enterohepatic circulation of baicalin in rats. | Xing, J., et al. 2005. Life Sci. 78: 140-6. PMID: 16107266
- Investigation of the absorption mechanisms of baicalin and baicalein in rats. | Taiming, L. and Xuehua, J. 2006. J Pharm Sci. 95: 1326-33. PMID: 16628739
- Comparative pharmacokinetics of baicalin after oral administration of pure baicalin, Radix scutellariae extract and Huang-Lian-Jie-Du-Tang to rats. | Lu, T., et al. 2007. J Ethnopharmacol. 110: 412-8. PMID: 17110066
- Protective effects of baicalin on ligature-induced periodontitis in rats. | Cai, X., et al. 2008. J Periodontal Res. 43: 14-21. PMID: 18230102
- Long-term baicalin administration ameliorates metabolic disorders and hepatic steatosis in rats given a high-fat diet. | Guo, HX., et al. 2009. Acta Pharmacol Sin. 30: 1505-12. PMID: 19890358
- Baicalin inhibits TLR2/4 signaling pathway in rat brain following permanent cerebral ischemia. | Tu, XK., et al. 2011. Inflammation. 34: 463-70. PMID: 20859668
- Protective effects of baicalin against ischemia/reperfusion injury in rat liver. | Kim, SJ., et al. 2010. J Nat Prod. 73: 2003-8. PMID: 21087019
- [Baicalin prevents the up-regulation of connective tissue growth factor in fibrotic lungs of rats]. | Jia, H., et al. 2010. Sheng Li Xue Bao. 62: 535-40. PMID: 21170500
- Baicalin protects mice from Staphylococcus aureus pneumonia via inhibition of the cytolytic activity of α-hemolysin. | Qiu, J., et al. 2012. J Infect Dis. 206: 292-301. PMID: 22551812
- Anti-NDV activity of baicalin from a traditional Chinese medicine in vitro. | Jia, Y., et al. 2016. J Vet Med Sci. 78: 819-24. PMID: 26902693
- The anti-inflammatory activity of Scutellaria rivularis extracts and its active components, baicalin, baicalein and wogonin. | Lin, CC. and Shieh, DE. 1996. Am J Chin Med. 24: 31-6. PMID: 8739179
- Baicalin, an inhibitor of HIV-1 production in vitro. | Kitamura, K., et al. 1998. Antiviral Res. 37: 131-40. PMID: 9588845
Inhibitor of:
β-defensin 2, ANT1, AQP8, CapZ-3, Coronavirus nucleocapsid, CRP, DC-SIGN, DC-SIGN/CD209, Fc ε RIγ, GADD 153, GILZ, Gram Negative Endotoxin Marker, HSV-1 gG, LBP1, LITAF, Olfr782, OPN1SW, PLP-Cγ, PR3, PREP, QSK, Retnlb, Thrombospondin 2, TIMP-3, TLR5, TNF-R2, Trav9n-3, V1RF5, and VSTM4.Activator of:
claudin-7, CLDN (Claudin), cryptdin 3, ERK 1, ERK 2, HSP 47, NPAL3, and Reg IIIδ.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Baicalin, 1 mg | sc-204638 | 1 mg | $55.00 | |||
Baicalin, 25 mg | sc-204638A | 25 mg | $110.00 | |||
Baicalin, 1 g | sc-204638B | 1 g | $220.00 | |||
Baicalin, 5 g | sc-204638C | 5 g | $260.00 |