Date published: 2026-3-10

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ZSWIM1 Activators

ZSWIM1, also known as Zinc Finger SWIM-Type Containing 1, is a protein encoded by the ZSWIM1 gene. The SWIM domain (SWI2/SNF2 and MuDR) is a zinc finger-like domain that is thought to mediate protein-protein interactions. These domains are typically found in a variety of proteins that are involved in chromatin remodeling, transcriptional regulation, and ubiquitin conjugation.

ZSWIM1 is ubiquitously expressed in various tissues, indicating that it may have a fundamental role in normal cellular physiology. The zinc finger motifs within the protein are characteristic of DNA binding or protein binding domains, implying that ZSWIM1 could interact with other proteins or with DNA to exert its function.Studies have hinted at possible involvement of ZSWIM1 in developmental processes and diseases. Alterations in the expression levels or mutations within the ZSWIM1 gene might be implicated in developmental disorders or pathologies. However, the evidence is not yet fully conclusive, and more research is needed to understand the full spectrum of ZSWIM1's physiological and pathological roles.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin activates adenylate cyclase, increasing cAMP levels, which enhances ZSWIM1 by promoting PKA activation, possibly influencing gene expression.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic Acid binds retinoic acid receptors, affecting gene transcription, which may upregulate ZSWIM1 expression through genomic signaling pathways.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$71.00
$163.00
$296.00
2
(1)

Vitamin D3 through its active metabolite, calcitriol, binds VDR, potentially influencing the expression of ZSWIM1 by modulating gene transcription.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

Trichostatin A is a histone deacetylase inhibitor that can enhance chromatin accessibility, possibly leading to increased ZSWIM1 transcription.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$218.00
$322.00
$426.00
7
(1)

As a DNA methyltransferase inhibitor, it reduces DNA methylation, potentially leading to the demethylation and activation of the ZSWIM1 gene.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

Sodium Butyrate, a histone deacetylase inhibitor, may promote ZSWIM1 expression by enhancing histone acetylation and transcriptional activation.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

Epigallocatechin Gallate inhibits DNA methyltransferases, which could result in hypomethylation and potential upregulation of ZSWIM1 expression.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol activates SIRT1, which may lead to changes in chromatin structure and impact the transcriptional regulation of ZSWIM1.

Zinc

7440-66-6sc-213177
100 g
$48.00
(0)

Zinc acts as a cofactor for DNA-binding proteins and may influence ZSWIM1 gene expression through modulation of transcription factor activity.

Copper(II) sulfate

7758-98-7sc-211133
sc-211133A
sc-211133B
100 g
500 g
1 kg
$46.00
$122.00
$189.00
3
(1)

Copper can act as a cofactor for various enzymes, potentially affecting the transcriptional regulation of genes like ZSWIM1.