ZNF862 Inhibitors
ZNF862 Inhibitors encompasses a range of chemicals designed to indirectly interfere with the roles of ZNF862 in transcription and DNA interactions. 5-Azacytidine and RG108, as DNA methyltransferase inhibitors, can modify the methylation state of DNA, possibly changing the affinity or interaction of ZNF862 with its targets. Histone modifications, which play a pivotal role in dictating chromatin state and DNA accessibility, can be influenced by compounds like Trichostatin A, Alphitolic acid, and SAHA. These agents, by altering chromatin structure, might affect the binding and function of ZNF862 in gene regulation.
The binding of ZNF862 to DNA may be directly competed or disrupted by agents like Mithramycin A, which preferentially targets GC-rich DNA regions. On the transcriptional machinery side, DRB and Actinomycin D can hinder RNA polymerase's activity, affecting any transcriptional activation or repression mediated by ZNF862. A-196, by inhibiting histone methyltransferases, adds another layer of chromatin modification that can influence the landscape in which ZNF862 operates.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNA methyltransferase inhibitor that can modify the methylation state of promoter regions, potentially affecting ZNF862-mediated transcription. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Histone deacetylase (HDAC) inhibitor that alters chromatin structure, possibly impacting DNA accessibility for ZNF862. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
Binds GC-rich DNA regions, which could alter ZNF862 binding to its DNA targets. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $43.00 $189.00 $316.00 $663.00 | 6 | |
Inhibits RNA polymerase II, impacting transcription where ZNF862 may act. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Binds DNA and interferes with RNA polymerase, potentially influencing ZNF862-mediated transcription. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $131.00 $515.00 | 2 | |
DNA methyltransferase inhibitor that can change DNA methylation, possibly affecting ZNF862 binding or activity. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
Another DNA methyltransferase inhibitor, which can influence gene expression and ZNF862 function. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
HDAC inhibitor that affects chromatin structure, possibly influencing the function of ZNF862 in transcription. | ||||||
Plumbagin | 481-42-5 | sc-253283 sc-253283A | 100 mg 250 mg | $52.00 $62.00 | 6 | |
Inhibits topoisomerase II, which may interfere with ZNF862's potential roles in DNA replication or repair. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Inhibits XPB, a subunit of the transcription factor TFIIH, impacting transcriptional processes where ZNF862 might be active. | ||||||