ZNF407 Inhibitors
ZNF407 inhibitors encompass a class of chemical compounds that modulate the activity of the ZNF407 zinc finger protein, albeit primarily through indirect mechanisms. Central to the function of zinc finger proteins is the presence of zinc ions. Therefore, chelating agents like TPEN, Dithizone, EDTA, and DTPA can deprive the cellular environment of zinc, impairing the proper folding and function of zinc finger proteins. On the flip side, compounds like Pyrithione elevate intracellular zinc levels, which can dysregulate zinc-requiring processes.
Another approach to influence zinc finger proteins is by targeting their interaction with DNA. Trifluoperazine, for instance, has shown the ability to hinder specific zinc finger protein-DNA associations. Moreover, the DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine, can alter the gene expression patterns of certain zinc finger proteins, affecting their regulation or activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dithizone | 60-10-6 | sc-206031A sc-206031 | 10 g 50 g | $92.00 $339.00 | 2 | |
A chelator that can bind to zinc, possibly affecting zinc finger protein function. | ||||||
Trifluoperazine Dihydrochloride | 440-17-5 | sc-201498 sc-201498A | 1 g 5 g | $57.00 $101.00 | 9 | |
An antipsychotic that has been shown to disrupt certain zinc finger protein-DNA interactions. | ||||||
Clioquinol | 130-26-7 | sc-201066 sc-201066A | 1 g 5 g | $45.00 $115.00 | 2 | |
An antifungal that can chelate zinc, potentially affecting zinc finger proteins. | ||||||
Diethylenetriaminepentaacetic acid | 67-43-6 | sc-214890 sc-214890A | 5 g 50 g | $75.00 $234.00 | 1 | |
Another chelating agent that can deplete cellular zinc, affecting zinc finger proteins indirectly. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
A DNA methyltransferase inhibitor which might influence the gene expression patterns of certain zinc finger proteins. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $53.00 $89.00 | 7 | |
It can bind and sequester zinc, potentially impacting zinc finger protein function. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
A dithiocarbamate fungicide that can bind to zinc, affecting its availability. | ||||||
Ebselen | 60940-34-3 | sc-200740B sc-200740 sc-200740A | 1 mg 25 mg 100 mg | $33.00 $136.00 $458.00 | 5 | |
An organoselenium compound known to affect various cellular pathways, including those involving zinc. | ||||||