ZNF208, or Zinc Finger Protein 208, is a protein that in humans is encoded by the ZNF208 gene. This protein is part of the Krüppel-like family of zinc finger proteins, which are transcription factors known for their role in DNA binding and the regulation of gene expression.
Zinc finger proteins are characterized by their finger-like folds, created by the coordination of a zinc ion with cysteine and histidine residues within the protein structure. These zinc finger domains enable the protein to interact with specific nucleic acid sequences, typically in the major groove of DNA. Such interactions can regulate the transcription of genes, affecting a variety of cellular processes including growth, development, differentiation, and apoptosis.ZNF208 contains multiple C2H2-type zinc finger domains, which is indicative of its potential to bind to many different DNA sequences and to have a role in regulating numerous genes. These proteins often function as sequence-specific repressors or activators of gene transcription, affecting the expression of genes involved in a wide range of biological processes.
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