Zfp846 inhibitors are a class of chemical compounds designed to target and regulate the function of the Zfp846 protein, which belongs to the family of zinc finger proteins. Zinc finger proteins, including Zfp846, are known for their role in DNA binding and gene regulation due to their structural zinc finger motifs, which enable them to interact with specific sequences of DNA. Zfp846 is involved in transcriptional regulation, meaning it influences the expression of various genes by interacting with their regulatory regions. Inhibitors of Zfp846 work by interfering with the protein's normal ability to bind DNA or interact with other molecular partners, thus blocking its influence on gene expression.
The structural diversity of Zfp846 inhibitors reflects the complexity of their interaction with the target protein. These compounds feature specific molecular arrangements that allow them to bind selectively to key regions of Zfp846, preventing its functional activity. By studying Zfp846 inhibitors, researchers gain valuable insights into the molecular pathways governed by this protein and the broader role it plays in maintaining cellular processes such as chromatin organization and transcriptional dynamics. The use of Zfp846 inhibitors in research provides a powerful tool for investigating protein-DNA interactions and the mechanisms underlying gene regulation, allowing for a deeper understanding of how zinc finger proteins contribute to the fine-tuned regulation of genetic expression within cells.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Inhibits the mTOR pathway, affecting proteins involved in gene regulation and cell growth, including Zfp846. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
A broad-spectrum kinase inhibitor, inhibiting kinases that phosphorylate or regulate Zfp846. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Inhibits PI3K, affecting downstream signaling pathways that involve Zfp846. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
Inhibits p38 MAPK, impacting Zfp846 if regulated by or interacting with this kinase. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
Inhibits MEK1/2, affecting Zfp846 if involved in the MAPK/ERK signaling pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, affecting Zfp846 if part of the JNK signaling pathway. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
PI3K inhibitor, affecting Zfp846 through downstream signaling pathways. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
Src family kinase inhibitor, indirectly affecting the function of Zfp846. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $105.00 $242.00 | 36 | |
Inhibits Protein Kinase C (PKC), impacting Zfp846 if associated with the PKC pathway. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
Inhibits NF-kB activation, impacting Zfp846 if it's involved in the NF-kB signaling pathway. | ||||||