Zfp788 Inhibitors
Zfp788 inhibitors encompass a range of compounds that indirectly influence the activity of the zinc finger protein 788 by targeting cellular pathways and processes that are crucial for its function. Cisplatin can bind to DNA and introduce crosslinks that hinder the DNA-binding capacity of transcription factors, including zinc finger proteins. This mechanism can disrupt Zfp788's ability to interact with its DNA targets. Similarly, chloroquine, which intercalates with nucleic acids, may obstruct the DNA-binding domain of Zfp788, thereby impairing its function as a transcription factor.
Compounds like triptolide and DRB exert their effects by inhibiting the transcriptional machinery, which can have downstream effects on transcription factors such as Zfp788, potentially limiting their capacity to modulate gene expression. Smithsonite, as a source of zinc, can disrupt zinc homeostasis when present in excessive concentrations, which is critical for the structural integrity of zinc finger domains in proteins like Zfp788.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
Binds to DNA and causes crosslinking, which can disrupt the DNA-binding activity of zinc finger transcription factors like Zfp788. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
A diterpenoid epoxide that can inhibit transcription and might affect the transcriptional activity of Zfp788. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Intercalates into DNA and RNA, which can interfere with the DNA-binding ability of zinc finger proteins like Zfp788. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $43.00 $189.00 $316.00 $663.00 | 6 | |
Inhibits transcription elongation, potentially affecting the regulatory functions of transcription factors like Zfp788. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An inhibitor of MEK, which is upstream of the ERK pathway; may alter transcription factor activity indirectly affecting the function of Zfp788. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
Selectively inhibits MEK1/2, affecting the MAPK/ERK pathway, which can modulate transcription factor activities and potentially Zfp788. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of the JNK pathway, which can influence transcription factor behavior and indirectly affect Zfp788. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
Inhibits p38 MAP kinase, potentially impacting transcription factor activity and thus the function of Zfp788. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor that can alter various signaling pathways, potentially affecting transcription factor activity including Zfp788. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor that can lead to changes in protein synthesis and transcription factor activity, possibly influencing Zfp788. | ||||||