ZFP161 Activators
ZFP161 Activators, also known as Zinc Finger Protein 161 Activators, represent a specific category of molecules that exert their biological effects by modulating the activity of the Zinc Finger Protein 161 (ZFP161). ZFP161 is a transcription factor, a type of protein that plays a crucial role in the regulation of gene expression. Transcription factors like ZFP161 are essential for controlling which genes are turned on or off in response to various cellular signals. ZFP161, in particular, is involved in the intricate and tightly regulated process of gene transcription, where genetic information encoded in DNA is transcribed into RNA, eventually leading to protein synthesis.
ZFP161 Activators are designed or naturally occurring compounds that interact with ZFP161 to enhance its transcriptional activity. This class of molecules can act in various ways to facilitate the binding of ZFP161 to specific DNA sequences, known as ZFP161 response elements, within the regulatory regions of target genes. By doing so, ZFP161 Activators can amplify the expression of these genes, effectively increasing the production of their corresponding proteins. This modulation of gene expression can have far-reaching consequences in cellular processes, as it can influence a wide array of biological functions, ranging from development and differentiation to responses to environmental signals. Understanding the mechanisms by which ZFP161 Activators function is of great interest to researchers, as it provides insights into the intricate web of gene regulation that underlies many biological processes. Researchers continue to investigate the precise chemical properties and interactions of ZFP161 Activators to unlock their full potential and elucidate their role in shaping the complex landscape of gene expression.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid is a vitamin A derivative that can activate ZFP161 by binding to its retinoic acid response elements (RAREs) in target gene promoters. This binding enhances the recruitment of transcriptional co-activators, leading to increased ZFP161-mediated gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
TSA is a histone deacetylase inhibitor. It indirectly activates ZFP161 by preventing the removal of acetyl groups from histones. This histone hyperacetylation allows for a more permissive chromatin structure, making ZFP161 more accessible to its target genes. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic acid is another histone deacetylase inhibitor that enhances ZFP161 activity by increasing histone acetylation. Like TSA, it promotes a chromatin environment that favors ZFP161-mediated gene expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates ZFP161 through the cAMP signaling pathway. It increases intracellular cAMP levels, which can lead to the phosphorylation and activation of transcription factors, including ZFP161, ultimately enhancing its transcriptional activity. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a DNA methyltransferase inhibitor. It activates ZFP161 by demethylating its target gene promoters, which can relieve gene silencing and promote ZFP161-mediated transcription. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $31.00 $117.00 $918.00 | 136 | |
DMSO is a solvent that can enhance ZFP161 activity by promoting the solubility and stability of ZFP161 or its co-factors, making it more effective in its role as a transcriptional activator. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol activates ZFP161 through various cellular signaling pathways. It can modulate gene expression by affecting transcriptional regulators and signaling molecules, indirectly promoting ZFP161-mediated gene activation. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate is a histone deacetylase inhibitor that can enhance ZFP161 activity by inhibiting histone deacetylation, leading to a more open chromatin structure that facilitates ZFP161 binding to target gene promoters. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin activates ZFP161 through its anti-inflammatory and antioxidant properties. It can modulate signaling pathways and transcription factors, indirectly promoting ZFP161-mediated gene expression. | ||||||
Thymoquinone | 490-91-5 | sc-215986 sc-215986A | 1 g 5 g | $47.00 $133.00 | 21 | |
Thymoquinone activates ZFP161 through various cellular mechanisms, potentially involving the modulation of transcriptional regulators and signaling pathways that enhance ZFP161's transcriptional activity. | ||||||