ZADH1 Inhibitors

ZADH1 inhibitors encompass a series of chemicals that predominantly target enzymes related to alcohol or aldehyde metabolism. Given that ZADH1 is categorized under the alcohol dehydrogenase domain-containing proteins, chemicals like 4-Methylpyrazole, Fomepizole, and Disulfiram can influence its enzymatic activity due to their established inhibitory effects on related enzymes. These compounds, by broadly targeting this enzyme class, provide avenues to modulate ZADH1 function.

Compounds like Cyanamide, Chlorpropamide, and Daidzin, known to primarily target aldehyde dehydrogenase, signify another group of molecules that can indirectly affect ZADH1 functionality. Additionally, enzyme modulators like Propargylamine and Hydroxylamine, with their general enzyme inhibition capabilities, present interactions with ZADH1. Notably, certain compounds, such as D-penicillamine and Pyrithione, can interfere with zinc-binding, and given ZADH1's zinc-binding domain, these agents provide a unique approach to influencing the protein's functionality.