XRCC6BP1 Inhibitors
XRCC6BP1 inhibitors primarily encompass a diverse set of compounds that are intricately linked with the processes of DNA repair, replication, and synthesis. For instance, Olaparib and Niraparib are recognized PARP inhibitors which predominantly act on DNA repair pathways. Their mode of action is to obstruct the repair of single-strand breaks, leading to double-strand breaks during replication.
Compounds like Etoposide and Camptothecin, which inhibit topoisomerase enzymes, have pivotal roles in unwinding DNA during replication and repair. Their inhibitory nature can hinder the normal progression of these processes. Consequently, any proteins, including XRCC6BP1, associated with these processes may have their activities modulated. Another perspective is brought in with compounds like NU7441, a DNA-PK inhibitor, which directly affects the non-homologous end joining pathway, a major DNA repair mechanism. Meanwhile, alkylating agents like Chlorambucil and Mitomycin C introduce cross-links in DNA, challenging the DNA repair machinery and potentially engaging XRCC6BP1 in the process.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Olaparib | 763113-22-0 | sc-302017 sc-302017A sc-302017B | 250 mg 500 mg 1 g | $206.00 $299.00 $485.00 | 10 | |
A PARP inhibitor which can influence DNA repair pathways. If XRCC6BP1 is involved in similar pathways, Olaparib can affect its function. | ||||||
Niraparib | 1038915-60-4 | sc-507492 | 10 mg | $150.00 | ||
Another PARP inhibitor affecting DNA repair processes. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
A topoisomerase II inhibitor that disrupts DNA replication and repair. Can impact XRCC6BP1 if it plays roles in these processes. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Inhibits topoisomerase I, affecting DNA replication and repair. Relevant if XRCC6BP1 has roles in these processes. | ||||||
ATM Kinase Inhibitor | 587871-26-9 | sc-202963 | 2 mg | $108.00 | 28 | |
An ATM kinase inhibitor which is central to DNA damage response. Might indirectly influence XRCC6BP1. | ||||||
NU 7441 | 503468-95-9 | sc-208107 | 5 mg | $350.00 | 10 | |
A DNA-PK inhibitor affecting non-homologous end joining, a DNA repair mechanism. If XRCC6BP1 is associated with this, NU7441 can be relevant. | ||||||
VE 821 | 1232410-49-9 | sc-475878 | 10 mg | $360.00 | ||
ATR kinase inhibitor. ATR is involved in DNA damage signaling. Can modulate XRCC6BP1 if it plays roles in this cascade. | ||||||
Chlorambucil | 305-03-3 | sc-204682 sc-204682A | 250 mg 1 g | $51.00 $120.00 | 3 | |
Alkylating agent causing DNA cross-links. Its effects on DNA can indirectly involve XRCC6BP1. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $65.00 $99.00 $140.00 | 85 | |
Causes DNA cross-links, leading to disruption in DNA repair processes which might involve XRCC6BP1. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
A pyrimidine analog that disrupts DNA synthesis and repair. Relevant if XRCC6BP1 plays roles in these pathways. | ||||||