Wnt-5b inhibitors belong to a distinct chemical class of compounds designed to specifically interact with and modulate the activity of the Wnt-5b protein. Wnt-5b is a member of the Wnt family of secreted glycoproteins that play a fundamental role in cellular signaling pathways governing various developmental and physiological processes. The inhibitors in this class are developed to bind selectively to Wnt-5b, altering its interactions with its receptors and downstream signaling cascades. Through their targeted modulation of Wnt-5b, these inhibitors offer a means for researchers to explore the intricate molecular mechanisms underlying cell fate determination, tissue morphogenesis, and other vital biological processes.
The study of Wnt-5b inhibitors provides a valuable tool to unravel the complexities of Wnt-5b signaling in different contexts. These inhibitors enable researchers to manipulate the activity of Wnt-5b and investigate its impact on cell behavior, migration, and differentiation. By perturbing Wnt-5b-mediated pathways, scientists can uncover insights into its involvement in tissue patterning, organ development, and other physiological phenomena. The use of Wnt-5b inhibitors contributes to advancing our understanding of the intricate molecular interactions that underlie normal cellular functions and various pathologies. Through the exploration of this chemical class, researchers aim to shed light on the complex interplay of molecular signals and pathways that govern cellular responses and contribute to the broader field of molecular and cellular biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
XAV939 | 284028-89-3 | sc-296704 sc-296704A sc-296704B | 1 mg 5 mg 50 mg | $35.00 $115.00 $515.00 | 26 | |
Tankyrase inhibitor affecting canonical Wnt signaling pathway, potentially influencing Wnt-5b signaling indirectly. | ||||||
IWP-2 | 686770-61-6 | sc-252928 sc-252928A | 5 mg 25 mg | $94.00 $286.00 | 27 | |
Porcupine inhibitor blocking secretion of various Wnt ligands, including Wnt-5b, affecting paracrine signaling. | ||||||
LGK 974 | 1243244-14-5 | sc-489380 sc-489380A | 5 mg 50 mg | $352.00 $1270.00 | 2 | |
Porcupine inhibitor that hampers secretion of Wnt ligands, possibly impacting Wnt-5b signaling similarly. | ||||||
Salinomycin | 53003-10-4 | sc-253530 sc-253530C sc-253530A sc-253530B | 5 mg 10 mg 25 mg 100 mg | $159.00 $236.00 $398.00 $465.00 | 1 | |
Polyether antibiotic inhibiting Wnt/β-catenin signaling, with potential indirect impact on Wnt-5b. | ||||||
NSC 668036 | 144678-63-7 | sc-507412 | 5 mg | $175.00 | ||
Compound with inhibitory effects on Wnt signaling, possibly influencing Wnt-5b function indirectly. | ||||||
PKF118-310 | 84-82-2 | sc-364590 sc-364590A | 5 mg 25 mg | $176.00 $638.00 | ||
Wnt/β-catenin signaling inhibitor, likely impacting Wnt-5b signaling indirectly. | ||||||
iCRT 14 | 677331-12-3 | sc-362746 sc-362746A | 10 mg 50 mg | $189.00 $771.00 | 9 | |
β-catenin-responsive transcription (CRT) inhibitor, affecting canonical Wnt pathway and Wnt-5b indirectly. | ||||||