WC1 inhibitors are a class of chemical compounds that play a significant role in the field of immunology, particularly in understanding the immune response of ruminant animals, such as cattle and sheep. These inhibitors target a specific protein known as WC1, which is predominantly found on the surface of γδ T cells in these animals. γδ T cells are a subset of T cells that are essential for the host's defense against various pathogens, including bacteria, viruses, and parasites. WC1 inhibitors are designed to modulate the activity of these γδ T cells by interfering with the WC1 protein's function.
The WC1 protein is unique to ruminant species and plays a pivotal role in regulating the immune response. WC1 inhibitors are utilized in research settings to better understand the complex interactions between γδ T cells and pathogens, as well as their involvement in immune surveillance and response. By selectively inhibiting WC1, scientists can gain insights into the precise mechanisms by which γδ T cells recognize and respond to antigens. This class of inhibitors has thus become an indispensable tool for immunologists, enabling them to unravel the intricacies of the immune system in ruminant animals and potentially providing valuable information for the development of novel strategies for disease control and vaccine development in veterinary medicine.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Fingolimod | 162359-55-9 | sc-507334 | 10 mg | $160.00 | ||
Fingolimod modulates S1P receptors, reducing lymphocyte migration and disrupting autoimmune responses. | ||||||
Dimethyl fumarate | 624-49-7 | sc-239774 | 25 g | $28.00 | 6 | |
Dimethyl fumarate activates the Nrf2 pathway, reducing inflammation and oxidative stress in immune cells. | ||||||
A77 1726 | 163451-81-8 | sc-207235 | 10 mg | $80.00 | 14 | |
Teriflunomide inhibits dihydroorotate dehydrogenase, leading to reduced pyrimidine synthesis and immune cell activity. | ||||||
2-Chloro-2′-deoxyadenosine | 4291-63-8 | sc-202399 | 10 mg | $144.00 | 1 | |
Cladribine is a purine analogue that interferes with DNA synthesis, impairing immune cell proliferation and function. | ||||||
Mycophenolate mofetil | 128794-94-5 | sc-200971 sc-200971A | 20 mg 100 mg | $37.00 $109.00 | 1 | |
Mycophenolate mofetil inhibits inosine monophosphate dehydrogenase, suppressing T and B cell proliferation. | ||||||
Azathioprine | 446-86-6 | sc-210853D sc-210853 sc-210853A sc-210853B sc-210853C | 500 mg 1 g 2 g 5 g 10 g | $203.00 $176.00 $349.00 $505.00 $704.00 | 1 | |
Azathioprine is converted to 6-mercaptopurine, which inhibits purine synthesis, leading to reduced immune cell activity. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $94.00 $213.00 | 33 | |
Methotrexate inhibits dihydrofolate reductase, disrupting DNA synthesis and reducing immune cell proliferation. | ||||||
Cyclophosphamide | 50-18-0 | sc-361165 sc-361165A sc-361165B sc-361165C | 50 mg 100 mg 500 mg 1 g | $90.00 $146.00 $469.00 $791.00 | 18 | |
Cyclophosphamide crosslinks DNA, causing cell death and suppressing the immune system's response to autoimmune disorders. | ||||||