Date published: 2026-4-1

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WC1 Inhibitors

WC1 inhibitors are a class of chemical compounds that play a significant role in the field of immunology, particularly in understanding the immune response of ruminant animals, such as cattle and sheep. These inhibitors target a specific protein known as WC1, which is predominantly found on the surface of γδ T cells in these animals. γδ T cells are a subset of T cells that are essential for the host's defense against various pathogens, including bacteria, viruses, and parasites. WC1 inhibitors are designed to modulate the activity of these γδ T cells by interfering with the WC1 protein's function.

The WC1 protein is unique to ruminant species and plays a pivotal role in regulating the immune response. WC1 inhibitors are utilized in research settings to better understand the complex interactions between γδ T cells and pathogens, as well as their involvement in immune surveillance and response. By selectively inhibiting WC1, scientists can gain insights into the precise mechanisms by which γδ T cells recognize and respond to antigens. This class of inhibitors has thus become an indispensable tool for immunologists, enabling them to unravel the intricacies of the immune system in ruminant animals and potentially providing valuable information for the development of novel strategies for disease control and vaccine development in veterinary medicine.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Fingolimod

162359-55-9sc-507334
10 mg
$160.00
(0)

Fingolimod modulates S1P receptors, reducing lymphocyte migration and disrupting autoimmune responses.

Dimethyl fumarate

624-49-7sc-239774
25 g
$28.00
6
(1)

Dimethyl fumarate activates the Nrf2 pathway, reducing inflammation and oxidative stress in immune cells.

A77 1726

163451-81-8sc-207235
10 mg
$80.00
14
(1)

Teriflunomide inhibits dihydroorotate dehydrogenase, leading to reduced pyrimidine synthesis and immune cell activity.

2-Chloro-2′-deoxyadenosine

4291-63-8sc-202399
10 mg
$144.00
1
(0)

Cladribine is a purine analogue that interferes with DNA synthesis, impairing immune cell proliferation and function.

Mycophenolate mofetil

128794-94-5sc-200971
sc-200971A
20 mg
100 mg
$37.00
$109.00
1
(1)

Mycophenolate mofetil inhibits inosine monophosphate dehydrogenase, suppressing T and B cell proliferation.

Azathioprine

446-86-6sc-210853D
sc-210853
sc-210853A
sc-210853B
sc-210853C
500 mg
1 g
2 g
5 g
10 g
$203.00
$176.00
$349.00
$505.00
$704.00
1
(1)

Azathioprine is converted to 6-mercaptopurine, which inhibits purine synthesis, leading to reduced immune cell activity.

Methotrexate

59-05-2sc-3507
sc-3507A
100 mg
500 mg
$94.00
$213.00
33
(5)

Methotrexate inhibits dihydrofolate reductase, disrupting DNA synthesis and reducing immune cell proliferation.

Cyclophosphamide

50-18-0sc-361165
sc-361165A
sc-361165B
sc-361165C
50 mg
100 mg
500 mg
1 g
$90.00
$146.00
$469.00
$791.00
18
(1)

Cyclophosphamide crosslinks DNA, causing cell death and suppressing the immune system's response to autoimmune disorders.