The term WC1 Activators refers to a category of compounds or molecules that have the ability to stimulate or modulate the activity of a specific cell surface receptor known as WC1. WC1 is a protein receptor primarily found on the surface of gamma delta T cells, a subset of T lymphocytes in the immune system. These receptors play a significant role in the recognition and response to various pathogens and antigens. WC1 receptors are particularly prevalent in cattle and certain other ruminants, where they are involved in the immune response against infections.
Activation of WC1 receptors by these activators can lead to a cascade of signaling events within the gamma delta T cells, ultimately influencing their effector functions. These functions may include the release of cytokines, cytotoxic activity, and the initiation of an immune response against invading microorganisms. WC1 activators can have varying effects on the immune response, depending on the specific context and the presence of other co-stimulatory signals. In conclusion, WC1 Activators represent a class of compounds that can modulate the activity of WC1 receptors on gamma delta T cells. These receptors are crucial for immune responses in certain animals, particularly ruminants, and their activation can influence various immune functions. Research into WC1 activators contributes to a better understanding of the immune system in these animals and may have implications for livestock health and immunology.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C, leading to cellular responses that could include upregulation of WC1 in immune cells. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D3 modulates immune function and could influence the expression of WC1 on gamma/delta T cells. | ||||||
Concanavalin A | 11028-71-0 | sc-203007 sc-203007A sc-203007B | 50 mg 250 mg 1 g | $119.00 $364.00 $947.00 | 17 | |
Con A is a plant lectin that can stimulate T cells and potentially increase WC1 expression. | ||||||
Zymosan | 9010-72-4 | sc-296863 sc-296863A | 100 mg 1 g | $99.00 $599.00 | 1 | |
Zymosan is a glucan from yeast cell walls that can activate the immune system, potentially upregulating WC1. | ||||||
Imiquimod | 99011-02-6 | sc-200385 sc-200385A | 100 mg 500 mg | $67.00 $284.00 | 6 | |
Imiquimod is an immune response modifier that may enhance WC1 expression through its immunostimulatory effects. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin has various biological activities, including modulation of immune responses, which may affect WC1 expression. | ||||||