Vmn2r95 Inhibitors
Vmn2r95 inhibitors pertain to a specialized category of chemical compounds that modulate the function of the Vmn2r95 receptor. This receptor is one of the numerous subtypes within the vomeronasal type-2 receptor (V2R) family, which plays a crucial role in the vomeronasal organ (VNO) of certain mammals. The VNO is primarily associated with the detection of pheromones, chemical signals that carry information between individuals of the same species, influencing social and reproductive behaviors. Vmn2r95 inhibitors, therefore, are chemicals that specifically bind to and inhibit the activity of the Vmn2r95 receptor, potentially altering the normal processing of these chemical cues.
The molecular architecture of Vmn2r95 inhibitors is designed to interact with the unique binding sites of the Vmn2r95 receptor. These inhibitors often mimic or competitively block the binding of the natural ligand, although the exact mechanism can vary depending on the specific inhibitor and its structure. The Vmn2r95 receptor's structure generally dictates the inhibitor's shape, charge distribution, and hydrophobic or hydrophilic properties, ensuring a precise fit that is essential for the inhibition to occur. By binding to the receptor, these inhibitors can modulate the receptor's conformation and prevent the typical signal transduction cascade within the VNO sensory neurons. The modulation of signal transduction by Vmn2r95 inhibitors can have a significant impact on the interpretation of pheromonal signals, which is a subject of interest in the study of intraspecies communication and the molecular underpinnings of such interactions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Palmitoylethanolamide | 544-31-0 | sc-202754 sc-202754A sc-202754B sc-202754C sc-202754D | 10 mg 50 mg 500 mg 1 g 10 g | $80.00 $243.00 $2091.00 $3339.00 $16657.00 | ||
As an endogenous fatty acid amide, it binds to peroxisome proliferator-activated receptor alpha (PPAR-α). Activation of PPAR-α can lead to modulation of olfactory receptor expression, which may indirectly inhibit Vmn2r95 by altering the receptor environment in which it operates. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Chloroquine is known to alkalinize intracellular vesicles, which can impair the function of G-protein coupled receptors such as Vmn2r95 by disrupting the receptor recycling process or ligand-receptor interaction due to pH sensitivity. | ||||||
Rimonabant | 168273-06-1 | sc-205491 sc-205491A | 5 mg 10 mg | $73.00 $163.00 | 15 | |
As a selective cannabinoid receptor type 1 (CB1) antagonist, it can modulate the olfactory system. This could indirectly affect Vmn2r95 by altering the signaling environment or receptor expression levels in the olfactory epithelium. | ||||||
JTE 907 | 282089-49-0 | sc-203616 sc-203616A | 10 mg 50 mg | $289.00 $1122.00 | ||
An inverse agonist for the cannabinoid receptor type 2 (CB2), which is expressed in the olfactory system. It may indirectly inhibit Vmn2r95 by modulating the olfactory signal transduction, which could alter the functional status of Vmn2r95. | ||||||
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $46.00 $122.00 $189.00 | 3 | |
Copper ions can directly bind to certain sites within olfactory receptors, potentially inhibiting Vmn2r95 by altering its structure or function. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc has been shown to inhibit olfactory signaling by binding to olfactory receptor proteins. This could lead to inhibition of Vmn2r95 by direct interaction with its ligand-binding site or conformational changes that affect its activity. | ||||||
Quinine | 130-95-0 | sc-212616 sc-212616A sc-212616B sc-212616C sc-212616D | 1 g 5 g 10 g 25 g 50 g | $79.00 $104.00 $166.00 $354.00 $572.00 | 1 | |
Known for its ability to affect taste receptors, quinine may also interact with olfactory receptors and could inhibit Vmn2r95 by changing its conformation or the receptor environment. | ||||||
Thioridazine | 50-52-2 | sc-473180 | 50 mg | $500.00 | ||
As an antagonist for multiple dopamine receptors, it could affect neurotransmission in the olfactory bulb. This may indirectly inhibit Vmn2r95 by modifying the overall signaling cascade that influences olfactory receptor function. | ||||||
Capsazepine | 138977-28-3 | sc-201098 sc-201098A | 5 mg 25 mg | $148.00 $459.00 | 11 | |
As a vanilloid receptor antagonist, it may influence the perception of sensory stimuli. Although its primary targets are not olfactory receptors, it could indirectly inhibit Vmn2r95 by affecting the signaling pathways in the sensory neurons. | ||||||
Suramin sodium | 129-46-4 | sc-507209 sc-507209F sc-507209A sc-507209B sc-507209C sc-507209D sc-507209E | 50 mg 100 mg 250 mg 1 g 10 g 25 g 50 g | $152.00 $214.00 $728.00 $2601.00 $10965.00 $21838.00 $41096.00 | 5 | |
It is a polysulfonated naphthylurea that inhibits various G-protein coupled receptors. Suramin may indirectly inhibit Vmn2r95 by altering downstream signaling pathways that affect the receptor's activity or expression. | ||||||