The conceptual class of Vmn2r87 Inhibitors encompasses a diverse array of chemical compounds that, through their action on various cellular signaling pathways and processes, have the potential to indirectly modulate the activity or expression of Vmn2r87. This receptor, belonging to the vomeronasal type 2 receptor family, plays a crucial role in the detection of pheromonal signals, with its activity being mediated through complex intracellular pathways characteristic of G protein-coupled receptors. Given the absence of direct inhibitors, the strategy employed focuses on altering the broader signaling landscape within which Vmn2r87 operates. By targeting key regulatory molecules and pathways-such as those involved in cAMP production, calcium signaling, and various kinase activities-these inhibitors can alter the cellular context and modulate the receptor's function. This approach not only provides a means to explore the biological functions of Vmn2r87 but also highlights the intricate web of cellular signaling pathways that govern sensory perception and response mechanisms at the molecular level.
Through this exploration, the selected compounds serve as tools for investigating the physiological roles of Vmn2r87 and the mechanisms by which it contributes to pheromone detection and signaling. This strategy underscores the complexity of signaling networks and the nuanced approaches required to influence receptor activity indirectly. The strategic selection of these compounds offers a foundation for probing the signaling pathways and processes underpinning Vmn2r87's function, facilitating a deeper understanding of the molecular underpinnings of sensory signaling. This methodology exemplifies the broader principles of signal transduction and cellular communication, emphasizing the potential of targeted chemical intervention to unravel the signaling dynamics of specialized receptors such as Vmn2r87, providing insights into the dynamic interplay of signals that drive cellular responses and behaviors.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Increases cAMP levels, potentially disrupting Vmn2r87-mediated signaling by overstimulation of the pathway. | ||||||
BAPTA/AM | 126150-97-8 | sc-202488 sc-202488A | 25 mg 100 mg | $138.00 $449.00 | 61 | |
Chelates intracellular Ca2+, potentially inhibiting Vmn2r87-related signal transduction dependent on calcium. | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $103.00 $293.00 $465.00 | 15 | |
A broad-spectrum PKC inhibitor, could disrupt downstream signaling pathways of Vmn2r87 by inhibiting kinase activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitor, affecting AKT signaling pathways that could be relevant to Vmn2r87's signaling context. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
MEK inhibitor, potentially blocking ERK pathway activation downstream of Vmn2r87. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
p38 MAPK inhibitor, might inhibit Vmn2r87-related stress response signaling. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor, could affect apoptosis pathways linked to Vmn2r87 signaling. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Another PI3K inhibitor, reinforcing the blockade of AKT pathway activation related to Vmn2r87. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $178.00 | 25 | |
Inhibits CaMKII, affecting calcium-dependent signaling pathways relevant to Vmn2r87. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
Src kinase inhibitor, potentially disrupting kinase-dependent signaling cascades relevant to Vmn2r87. | ||||||