Vmn2r19 Inhibitors
Vmn2r19 inhibitors include a diverse range of chemical compounds that exert their effects by modulating various aspects of the olfactory signaling pathways. Compounds like quinpirole and SCH-23390 target dopamine receptors, which play a role in the modulation of olfactory processing, thus indirectly affecting the activity of Vmn2r19. Dopamine receptor agonists or antagonists can alter neuronal pathways that are crucial for the normal function of olfactory receptors, leading to potential inhibition. Similarly, chemicals like phenylthiourea (PTU), capsaicin, and menthol, which are known to influence taste perception and temperature sensation, respectively, can also modulate the activity of sensory neurons, including those in the olfactory system. These sensory modulators might interfere with the functional activity of Vmn2r19 by altering the cross-modal processing that occurs between different sensory systems.
Furthermore, compounds such as methyl anthranilate and metal sulfates like copper sulfate, zinc sulfate, and silver nitrate can cause damage to the olfactory epithelium or impair olfactory function, which would indirectly inhibit the signaling of Vmn2r19. Anosmia-inducing agents, by affecting the structural integrity of the olfactory epithelium, can lead to a decreased activity of olfactory receptors. Heavy metals such as cadmium chloride also contribute to olfactory impairment and are likely to inhibit Vmn2r19 activity by their toxic effects on the olfactory system. Additionally, natural compounds like limonene and cinnamaldehyde, known for their scent properties, may influence olfactory receptor activity, including Vmn2r19, by affecting the signaling mechanisms within the olfactory pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Quinpirole hydrochloride | 85798-08-9 | sc-253339 | 10 mg | $138.00 | 1 | |
A dopamine receptor agonist known to selectively activate D2-like receptors which are implicated in the modulation of the olfactory system. The activation of these receptors can inhibit the signaling of Vmn2r19 by altering the neuronal pathways associated with olfactory processing. | ||||||
SCH 23390 | 125941-87-9 | sc-200408 sc-200408A | 5 mg 25 mg | $175.00 $719.00 | 2 | |
A selective dopamine D1 receptor antagonist. By blocking D1 receptors, SCH-23390 can indirectly affect the olfactory signaling pathways in which Vmn2r19 is involved, potentially inhibiting its functional activity. | ||||||
N-Phenylthiourea | 103-85-5 | sc-236086 | 100 g | $319.00 | ||
A compound that alters taste perception by inhibiting phenylthiocarbamide (PTC) tasting, which may have a cross-modal effect on olfactory receptors such as Vmn2r19, potentially inhibiting its activity. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $94.00 $173.00 $255.00 $423.00 | 26 | |
An active component of chili peppers that binds to TRPV1 receptors, which are involved in the sensation of heat and pain. Capsaicin indirectly influences olfactory receptor neurons, which could interfere with the functional activity of Vmn2r19. | ||||||
(±)-Menthol | 89-78-1 | sc-250299 sc-250299A | 100 g 250 g | $38.00 $67.00 | ||
A compound that activates TRPM8 receptors, involved in the sensation of cold. Similar to capsaicin, menthol can modulate sensory neurons and may indirectly inhibit the signaling of Vmn2r19. | ||||||
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $45.00 $120.00 $185.00 | 3 | |
Known to cause anosmia in fish by damaging their olfactory epithelium. It could indirectly inhibit the functional activity of Vmn2r19 by affecting the olfactory sensory neurons. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
A chemical known to induce anosmia in animals by damaging the olfactory epithelium which could lead to the inhibition of olfactory receptors such as Vmn2r19. | ||||||
Silver nitrate | 7761-88-8 | sc-203378 sc-203378A sc-203378B | 25 g 100 g 500 g | $112.00 $371.00 $1060.00 | 1 | |
Used historically to induce anosmia. It can damage the olfactory epithelium, potentially inhibiting the functional activity of Vmn2r19. | ||||||
Cadmium chloride, anhydrous | 10108-64-2 | sc-252533 sc-252533A sc-252533B | 10 g 50 g 500 g | $55.00 $179.00 $345.00 | 1 | |
A heavy metal that can cause olfactory impairment by affecting the olfactory system, which may lead to the inhibition of receptors like Vmn2r19. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $82.00 $126.00 | 3 | |
A citrus scent compound that can modulate olfactory receptor activity. It may indirectly inhibit Vmn2r19 by affecting the signaling pathways within the olfactory system. | ||||||