VEGF-B Inhibitors
VEGF-B inhibitors belong to a class of compounds designed to target and modulate the activity of vascular endothelial growth factor B (VEGF-B), a specific member of the VEGF family of proteins. These inhibitors are developed primarily for their sbility to influence angiogenesis and vascular functions in the body. VEGF-B is known to play a role in the regulation of blood vessel formation, particularly in cardiac and skeletal muscle tissues. Therefore, VEGF-B inhibitors are designed to block or reduce the activity of this growth factor, which may have implications in various physiological processes.
VEGF-B inhibitors are typically small molecules or monoclonal antibodies that specifically interact with VEGF-B or its receptors, preventing the downstream signaling pathways associated with VEGF-B activation. By doing so, these inhibitors may affect processes such as angiogenesis, vasculogenesis, and the maintenance of existing blood vessels. The precise mechanisms of action can vary among different VEGF-B inhibitors, but the overarching goal is to modulate vascular development and function. Understanding the properties and effects of VEGF-B inhibitors at the molecular level is crucial for their application in various biomedical contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin, also known as sirolimus, inhibits the mTOR pathway, which is involved in cell growth and proliferation, potentially leading to a reduction in VEGF-B expression. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $57.00 $100.00 $250.00 | 129 | |
Sorafenib targets multiple tyrosine kinases and has been shown to inhibit angiogenesis, possibly reducing VEGF-B levels indirectly. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, a compound found in turmeric, has anti-inflammatory and antioxidant properties, and may down-regulate VEGF-B expression through various signaling pathways. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol is a natural compound found in grapes, with antioxidant properties, and it might suppress VEGF-B expression by modulating related signaling pathways. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
DL-Sulforaphane has demonstrated the ability to modulate gene expression, potentially including the down-regulation of VEGF-B. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is a flavonoid with anti-inflammatory effects, and it has been suggested to influence the expression of various genes, possibly including VEGF-B. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
DL-Sulforaphane, a major component of green tea, has been studied for its potential to modulate gene expression and may impact the levels of VEGF-B. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid, found in vitamin A, plays a role in cell growth and differentiation, and it may have the potential to influence VEGF-B expression. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine is an alkaloid found in several plants, with multiple biological activities, and it may impact the expression of VEGF-B. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $58.00 $95.00 $245.00 $727.00 | 8 | |
Found in fruits and nuts, ellagic acid has antioxidant properties and might modulate gene expression, including potentially down-regulating VEGF-B. | ||||||