VDAC3 Activators
VDAC3 activators belong to a class of chemical compounds that specifically target the Voltage-Dependent Anion Channel 3 (VDAC3), a mitochondrial protein that plays a crucial role in regulating the transport of ions, metabolites, and other molecules across the mitochondrial outer membrane. These activators are designed to modulate the activity of VDAC3, which is an essential component of the mitochondrial permeability transition pore (mPTP) complex, influencing mitochondrial function and cellular physiology. VDAC3, a member of the VDAC protein family, is primarily located on the outer mitochondrial membrane and is involved in mediating the exchange of metabolites, including adenosine triphosphate (ATP) and various ions, between the mitochondria and the cytoplasm.
The activation of VDAC3 by specific chemical compounds can have a profound impact on mitochondrial function and, consequently, cellular processes such as energy production, apoptosis, and cell signaling. VDAC3 activators are designed to modulate the opening and closing of the VDAC3 channel, thereby influencing the passage of molecules through the mitochondrial outer membrane. This modulation can alter the balance of ions and metabolites within the mitochondria, which, in turn, can affect cellular bioenergetics, mitochondrial dynamics, and cell fate decisions. Understanding the mechanisms and effects of VDAC3 activators is of significant interest in the field of cell biology and mitochondrial research, as it can shed light on fundamental processes related to mitochondrial function and cell physiology.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol may enhance VDAC3 expression by modulating mitochondrial functions and oxidative stress response, which is crucial for cellular energy balance. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin potentially induces VDAC3 expression by influencing mitochondrial dynamics and apoptosis pathways, often linked with cellular stress responses. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $42.00 $62.00 $153.00 $255.00 $500.00 $30.00 | 37 | |
1,1-Dimethylbiguanide, Hydrochloride might upregulate VDAC3 as part of its role in modulating mitochondrial metabolism and energy homeostasis in cells. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane could induce VDAC3 expression through its impact on cellular oxidative stress and mitochondrial function, which are key areas of VDAC3 involvement. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin may increase VDAC3 levels by affecting mitochondrial biogenesis and function, closely linked to VDAC3's role in metabolite transport. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG potentially modulates VDAC3 expression via its effects on mitochondrial function and cellular antioxidant mechanisms. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Caffeine might influence VDAC3 expression by altering cellular energy metabolism and mitochondrial activity, which are processes where VDAC3 is involved. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
Nicotinamide could upregulate VDAC3 through its role in cellular energy metabolism and mitochondrial function, both of which are key areas where VDAC3 operates. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid may affect VDAC3 expression by modulating gene expression and mitochondrial activity, which are crucial for VDAC3's function in the cell. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Cholecalciferol potentially enhances VDAC3 expression through its regulatory role in cellular metabolism and mitochondrial function, both of which are linked to VDAC3 activity. | ||||||