The chemical class designated as VCX-B1 Inhibitors comprises a group of compounds meticulously designed to selectively target VCX-B1, a molecular entity intricately linked to reproductive biology and male fertility. VCX-B1, or Variable Charge X-linked protein-B1, is a member of the VCX gene family located on the X chromosome. The specific functions and regulatory mechanisms of VCX-B1 are areas of active investigation within the field of reproductive genetics. While the broader VCX family is acknowledged for its involvement in spermatogenesis and male reproductive health, the unique characteristics of VCX-B1 and its precise role in cellular processes remain subjects of exploration for researchers. Inhibitors within the VCX-B1 Inhibitors class are intricately engineered molecules with the primary goal of modulating the activity or function of VCX-B1, thereby inducing an inhibitory effect. Researchers in this field employ a multidisciplinary approach, integrating insights from molecular genetics, structural biology, and medicinal chemistry to comprehend the complex molecular interactions between the inhibitors and the target VCX-B1.
Structurally, VCX-B1 Inhibitors are characterized by specific molecular features tailored to facilitate selective binding to VCX-B1. This selectivity is crucial to minimize unintended effects on other VCX family members or cellular components, ensuring a focused impact on the intended molecular target. The development of inhibitors within this chemical class involves a comprehensive exploration of structure-activity relationships, optimization of pharmacokinetic properties, and a deep understanding of the molecular mechanisms associated with VCX-B1. As researchers delve deeper into the functional aspects of VCX-B1 Inhibitors, the knowledge generated contributes not only to deciphering the specific roles of Variable Charge X-linked protein-B1 but also to advancing our broader comprehension of male reproductive biology and the intricate molecular events governing fertility processes. The exploration of VCX-B1 Inhibitors stands as a significant avenue for expanding fundamental knowledge in reproductive genetics and cellular physiology.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Can cause hypomethylation of DNA, possibly affecting gene expression patterns, including those of genes like VCX-B1. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
A DNA methyltransferase inhibitor that may alter gene expression, which could impact the transcription of VCX-B1. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
A histone deacetylase inhibitor that could potentially alter the expression of a wide range of genes, including VCX-B1. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Another histone deacetylase inhibitor, could change chromatin accessibility and gene expression profiles. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Binds to specific DNA sequences, potentially preventing the binding of transcription factors necessary for VCX-B1 expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inhibits mTOR and may indirectly affect the expression of various genes, potentially including VCX-B1. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Through its receptors, retinoic acid modulates gene expression, which may influence VCX-B1 transcription. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
As a PI3K inhibitor, this compound can disrupt downstream signaling pathways, possibly affecting gene expression. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Intercalates into DNA and inhibits RNA polymerase, decreasing the transcription of a wide array of genes. | ||||||
Spironolactone | 52-01-7 | sc-204294 | 50 mg | $107.00 | 3 | |
Has the potential to modulate transcriptional activity and could thus impact the expression of certain genes. |