Date published: 2026-1-9

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TTF-1 Antibodies

Santa Cruz Biotechnology delivers a wide array of TTF-1 monoclonal antibodies for research focused on understanding TTF-1 protein function. The monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). TTF-1, or thyroid transcription factor-1, is a critical protein involved in the regulation of gene expression in the thyroid, lung, and brain. TTF-1 plays a significant role in the development and function of these organs, making it an important target for research in developmental biology and disease states, particularly in lung cancer and thyroid disorders. Understanding TTF-1 function can provide insights into various pathophysiological conditions and aid in the development of targeted therapies. TTF-1 monoclonal antibodies enable researchers to explore cellular pathways and molecular mechanisms involved in organ development and disease progression. Investigating TTF-1 expression patterns and interactions helps advance our understanding of tissue-specific gene regulation and developmental processes. The high specificity of TTF-1 monoclonal antibodies supports precise detection and characterization of TTF-1 in research samples. Santa Cruz Biotechnology monoclonal antibodies for TTF-1 research contribute to advancing scientific knowledge in developmental biology, cancer research, and therapeutic development.

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TTF-1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

TTF-1/Thyroid Transcription Factor 1/NKX2-1 Antibody (8G7G3/1)

sc-53136mouse IgG1 κFL (r)WB, IP, IF, IHC(P), ELISAm, r, h
30
(14)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 Antibody (F-12)

sc-25331mouse IgG1 κ1-190 (h)WB, IP, IF, ELISAm, r, h
6
(6)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 Antibody (E-4)

sc-514992mouse IgG1 κ7-28 (h)WB, IP, IF, ELISAm, r, h
1
(0)

TTF-1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TTF-1/Thyroid Transcription Factor 1/NKX2-1 CRISPR/Cas9 KO Plasmid (h)

sc-400458hGene KnockoutGFP0
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 CRISPR/Cas9 KO Plasmid (h2)

sc-400458-KO-2hGene KnockoutGFP0
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 HDR Plasmid (h2)

sc-400458-HDR-2hHomology Directed RepairPuromycin0
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 Double Nickase Plasmid (h)

sc-400458-NIChGene KnockoutPuromycin0
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 Double Nickase Plasmid (h2)

sc-400458-NIC-2hGene KnockoutPuromycin0
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 CRISPR/Cas9 KO Plasmid (m)

sc-423405mGene KnockoutGFP0
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 HDR Plasmid (m)

sc-423405-HDRmHomology Directed RepairPuromycin0
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 Double Nickase Plasmid (m)

sc-423405-NICmGene KnockoutPuromycin0
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 Double Nickase Plasmid (m2)

sc-423405-NIC-2mGene KnockoutPuromycin0
(0)

TTF-1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TTF-1/Thyroid Transcription Factor 1/NKX2-1 CRISPR Activation Plasmid (h)

sc-400458-ACThGene ActivationPuro, Blast, Hygro0
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 CRISPR Activation Plasmid (h2)

sc-400458-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 Lentiviral Activation Particles (h)

sc-400458-LAChGene ActivationPuro, Blast, Hygro0
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 Lentiviral Activation Particles (h2)

sc-400458-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 CRISPR Activation Plasmid (m)

sc-423405-ACTmGene ActivationPuro, Blast, Hygro0
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 CRISPR Activation Plasmid (m2)

sc-423405-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 Lentiviral Activation Particles (m)

sc-423405-LACmGene ActivationPuro, Blast, Hygro0
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 Lentiviral Activation Particles (m2)

sc-423405-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

TTF-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TTF-1/Thyroid Transcription Factor 1/NKX2-1 siRNA (h)

sc-36756hGene SilencingN/A
1
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 shRNA Plasmid (h)

sc-36756-SHhGene SilencingPuromycin
1
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 shRNA (h) Lentiviral Particles

sc-36756-VhGene SilencingPuromycin
1
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 siRNA (m)

sc-36757mGene SilencingN/A
2
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 shRNA Plasmid (m)

sc-36757-SHmGene SilencingPuromycin
2
(0)

TTF-1/Thyroid Transcription Factor 1/NKX2-1 shRNA (m) Lentiviral Particles

sc-36757-VmGene SilencingPuromycin
2
(0)