TPPP3 Inhibitors
TPPP3 inhibitors belong to a distinct chemical class of compounds that have been identified for their unique ability to modulate the activity of the enzyme TPPP3, also known as tubulin polymerization-promoting protein family member 3. TPPP3 is a crucial regulatory protein involved in the stabilization and dynamics of microtubules within cells, playing a pivotal role in various cellular processes. The inhibitors are designed to selectively interact with TPPP3, leading to the inhibition of its enzymatic function, without affecting other cellular components or interfering with other essential biological pathways.
The molecular structure of TPPP3 inhibitors is characterized by specific functional groups and arrangements that enable them to bind to the active site of the TPPP3 enzyme with high affinity, thereby preventing its normal catalytic activity. As a result of this interaction, the dynamic organization of microtubules within the cell may be altered, potentially influencing various cellular processes that rely on microtubule function. The identification and development of TPPP3 inhibitors open up new avenues for understanding the fundamental mechanisms governing microtubule dynamics and may hold promise for further advancements in basic cell biology research.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Albendazole | 54965-21-8 | sc-210771 | 100 mg | $209.00 | 1 | |
Although primarily known as an antiparasitic agent, Albendazole has also been found to inhibit TPPP3, contributing to its anti-cancer properties. | ||||||
Dimethyl fumarate | 624-49-7 | sc-239774 | 25 g | $27.00 | 6 | |
Dimethyl fumarate (CAS 624-49-7) is a small molecule that functions as an inhibitor of the TPPP3 protein. It achieves this by interacting with specific binding sites on TPPP3, altering its structure and disrupting its normal function in microtubule dynamics. This inhibition can affect cellular processes involving microtubule stabilization and assembly, providing valuable insights into the regulation of cytoskeletal components in scientific research. | ||||||
Mebendazole | 31431-39-7 | sc-204798 sc-204798A | 5 g 25 g | $45.00 $87.00 | 2 | |
Mebendazole (CAS 31431-39-7) functions as an inhibitor of the TPPP3 protein, which is involved in microtubule dynamics and stabilization. By disrupting TPPP3 activity, Mebendazole interferes with microtubule organization, impacting the protein′s ability to promote microtubule polymerization. This mechanism is of interest for research into the regulation of cytoskeletal functions and cellular processes reliant on microtubule integrity. | ||||||
Docetaxel | 114977-28-5 | sc-201436 sc-201436A sc-201436B | 5 mg 25 mg 250 mg | $85.00 $325.00 $1072.00 | 16 | |
Docetaxel (CAS 114977-28-5) is a chemical known for its role as an inhibitor of the TPPP3 protein. It interferes with the polymerization of tubulin, a key component of the microtubule structure, which impacts the function of TPPP3. By disrupting microtubule dynamics, Docetaxel affects the stability and activity of TPPP3 in cellular processes, making it a valuable tool for research into protein-microtubule interactions. | ||||||
Estramustine | 2998-57-4 | sc-353281 sc-353281A | 100 mg 1 g | $265.00 $743.00 | ||
Estramustine (CAS 2998-57-4) is a chemical compound that acts as an inhibitor of TPPP3, a tubulin polymerization-promoting protein. Through its interaction, Estramustine disrupts the normal function of TPPP3, influencing microtubule dynamics and potentially altering cellular processes involving the cytoskeleton. This makes it a valuable tool in scientific research for studying protein interactions and the regulation of microtubule stability. | ||||||