TMEM211 Inhibitors

LHFPL tetraspan subfamily member 7, designated as LHFPL7, belongs to the LHFPL family of proteins, which are characterized by their four hydrophobic transmembrane domains, making them part of the broader class of tetraspan transmembrane proteins. The LHFPL7 protein is encoded by the LHFPL7 gene located on chromosome 19 in humans.While detailed functional insights of LHFPL7 are not as extensively documented as those of some other tetraspan proteins, members of this family are generally implicated in a variety of cellular processes. These processes typically involve the modulation of cell signaling, trafficking of other membrane proteins, and contributing to the structure and maintenance of various cellular membranes.

LHFPL7, like its family members, is thought to play a role in the formation of complexes at cell membranes that are crucial for cell-to-cell communication and signal transduction. The tetraspan nature of LHFPL7 suggests a functional involvement in organizing the architecture of membrane domains, potentially influencing the assembly of signaling complexes or acting as scaffolds for receptor stabilization.Given the structural characteristics of tetraspanins, LHFPL7 may participate in the clustering of specific sets of proteins, such as receptors or ion channels, thereby influencing their functional properties. This could affect processes such as synaptic transmission or sensory perception, where precise membrane protein organization is critical.