The chemical class of TIP47 Activators encompasses a diverse range of compounds that can indirectly influence the activity of TIP47, a protein pivotal in lipid droplet formation and lipid metabolism. These chemicals, through various mechanisms, modulate lipid metabolic pathways and processes, thereby potentially affecting the function and regulation of TIP47.
Compounds such as forskolin, isoproterenol, and caffeine, which enhance lipolysis through the cAMP pathway, can indirectly influence TIP47 by altering the dynamics of lipid droplet formation and metabolism. Similarly, metabolic regulators like NAD+ and acetyl-CoA are central to lipid metabolism, and their levels can have a consequential impact on TIP47 activity. The involvement of omega-3 fatty acids, specifically eicosapentaenoic acid, in modulating lipid metabolism further highlights the interplay between dietary components and lipid metabolic pathways, potentially influencing TIP47 function. PPAR-gamma agonists, including rosiglitazone and pioglitazone, known for their role in enhancing insulin sensitivity, also modulate lipid metabolism, thereby indirectly affecting TIP47. Additionally, AMPK activators like AICAR and metformin, key regulators of energy balance, influence lipid metabolism, which could impact TIP47 activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylate cyclase, increasing cAMP levels. Elevated cAMP can enhance lipolysis and potentially influence lipid droplet formation, indirectly affecting TIP47 activity. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $27.00 $37.00 | 5 | |
A beta-adrenergic agonist that stimulates lipolysis via cAMP pathway activation, potentially influencing TIP47's role in lipid droplet formation and metabolism. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $56.00 $186.00 $296.00 $655.00 $2550.00 $3500.00 $10500.00 | 4 | |
Involved in redox reactions, NAD+ can influence metabolic pathways including those involving lipids, potentially impacting TIP47 activity. | ||||||
Acetyl coenzyme A trisodium salt | 102029-73-2 | sc-210745 sc-210745A sc-210745B | 1 mg 5 mg 1 g | $46.00 $80.00 $5712.00 | 3 | |
Central to lipid metabolism. Alterations in acetyl-CoA levels can influence lipid synthesis and turnover, potentially affecting TIP47 activity. | ||||||
Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) | 10417-94-4 | sc-200766 sc-200766A | 100 mg 1 g | $102.00 $423.00 | ||
Omega-3 fatty acids can modulate lipid metabolism pathways, potentially influencing the activity of TIP47 in lipid droplet formation and function. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
A PPAR-gamma agonist used to enhance insulin sensitivity. By modulating lipid metabolism, rosiglitazone can indirectly affect TIP47 activity. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
Another PPAR-gamma agonist that enhances insulin sensitivity and influences lipid metabolism, potentially affecting TIP47. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Stimulates lipolysis by inhibiting phosphodiesterase, which leads to increased cAMP levels, potentially influencing TIP47 activity. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
Activates AMPK, a key regulator of energy balance. AMPK activation can influence lipid metabolism, potentially impacting TIP47. | ||||||
Exendin-4 | 141758-74-9 | sc-474611 sc-474611A | 500 µg 1 mg | $143.00 $194.00 | 1 | |
GLP-1 analogs enhance insulin secretion and modulate lipid metabolism, which may influence TIP47 activity. | ||||||