Date published: 2026-3-9

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Tie-2 Antibodies

Santa Cruz Biotechnology provides a broad selection of Tie-2 monoclonal antibodies for research focused on understanding Tie-2 receptor functions in biological processes. Tie-2 Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The Tie-2 receptor, also known as TEK, plays a crucial role in angiogenesis and vascular stability, significantly impacting endothelial cell function and survival. Tie-2 signaling pathways are essential in maintaining vascular health and have been linked to various conditions including cancer, cardiovascular diseases, and inflammatory disorders. Research into Tie-2 mechanisms continues to reveal new possibilities for therapeutic interventions. Understanding Tie-2's molecular interactions provides valuable insights into disease progression and potential treatment approaches. Investigating Tie-2's role in vascular development has opened new avenues for medical research and drug development. Santa Cruz Biotechnology monoclonal antibodies for Tie-2 research support scientists worldwide in advancing our understanding of vascular biology and disease treatment.

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Tie-2 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Tie-2 Antibody (F-6)

sc-518076mouse IgM κ65-88 (h)WB, IP, IF, ELISAh

new

(1)

Tie-2 Antibody (F-8)

sc-518137mouse IgM κ816-836 (h)WB, IP, IF, ELISAh

new

(1)

Tie-2 Antibody (3A5)

sc-293414mouse IgG2a κ66-185 (h)WB, IP, ELISAm, r, h
11
(4)

Tie-2 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Tie-2 CRISPR/Cas9 KO Plasmid (h)

sc-400295hGene KnockoutGFP0
(0)

Tie-2 HDR Plasmid (h)

sc-400295-HDRhHomology Directed RepairPuromycin0
(0)

Tie-2 CRISPR/Cas9 KO Plasmid (m)

sc-423334mGene KnockoutGFP0
(0)

Tie-2 HDR Plasmid (m)

sc-423334-HDRmHomology Directed RepairPuromycin0
(0)

Tie-2 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Tie-2 CRISPR Activation Plasmid (h)

sc-400295-ACThGene ActivationPuro, Blast, Hygro0
(0)

Tie-2 CRISPR Activation Plasmid (h2)

sc-400295-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Tie-2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Tie-2 siRNA (h)

sc-36677hGene SilencingN/A
10
(0)

Tie-2 shRNA Plasmid (h)

sc-36677-SHhGene SilencingPuromycin
10
(0)

Tie-2 shRNA (h) Lentiviral Particles

sc-36677-VhGene SilencingPuromycin
10
(0)

Tie-2 siRNA (m)

sc-36678mGene SilencingN/A
4
(0)

Tie-2 shRNA Plasmid (m)

sc-36678-SHmGene SilencingPuromycin
4
(0)

Tie-2 shRNA (m) Lentiviral Particles

sc-36678-VmGene SilencingPuromycin
4
(0)