Date published: 2025-12-19

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TEX33 Inhibitors

TEX33 inhibitors are a class of chemical compounds that specifically target the TEX33 protein, a member of the testis-expressed protein family. TEX33, though predominantly expressed in testicular tissue, has been identified as playing a role in various cellular processes, including protein interactions and potentially in the regulation of gene expression during meiosis and other cell-specific functions. TEX33 is characterized by its distinct domain architecture, which allows it to engage with other proteins, contributing to complex cellular networks. Inhibitors of TEX33 work by disrupting these protein-protein interactions, interfering with its ability to function within these cellular networks. This disruption could alter the molecular dynamics within cells, affecting the pathways that depend on TEX33's proper functioning.

By inhibiting TEX33, these compounds can impact several key biological processes associated with its function in testis-specific or broader cellular contexts. TEX33 may play a role in the coordination of protein assembly or localization within certain cell types, and its inhibition can disrupt these processes. This disruption can manifest in altered protein homeostasis or signal transduction, leading to potential downstream effects on cellular function. Furthermore, TEX33's involvement in cellular pathways that are not fully elucidated makes inhibitors of this protein valuable tools for studying its exact molecular role. By selectively targeting TEX33, researchers can gain insights into its biochemical interactions and better understand the broader impact of testis-expressed proteins on cellular biology. The specificity of these inhibitors allows for detailed investigation into the cellular mechanisms regulated by TEX33, providing a deeper understanding of its contributions to cellular organization and function.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

Cycloheximide inhibits eukaryotic protein synthesis, potentially decreasing the expression of ciliary microtubule-associated proteins.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Rapamycin inhibits mTOR, a kinase involved in protein synthesis; this could reduce the expression of proteins essential for cilia function.

Doxorubicin

23214-92-8sc-280681
sc-280681A
1 mg
5 mg
$173.00
$418.00
43
(3)

Doxorubicin intercalates DNA, potentially disrupting transcription and thus inhibiting protein expression related to cilia.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Actinomycin D binds to DNA and halts mRNA synthesis, which can inhibit the expression of ciliary proteins.

Chloroquine

54-05-7sc-507304
250 mg
$68.00
2
(0)

Chloroquine can alter endosomal and lysosomal pH, which might affect protein trafficking and expression in ciliary assembly.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

5-Azacytidine incorporates into RNA and DNA, potentially modulating gene expression patterns, including those for ciliary proteins.

Taxol

33069-62-4sc-201439D
sc-201439
sc-201439A
sc-201439E
sc-201439B
sc-201439C
1 mg
5 mg
25 mg
100 mg
250 mg
1 g
$40.00
$73.00
$217.00
$242.00
$724.00
$1196.00
39
(2)

Paclitaxel stabilizes microtubules and could disrupt the dynamic needed for proper cilia function and protein expression.

Vinblastine

865-21-4sc-491749
sc-491749A
sc-491749B
sc-491749C
sc-491749D
10 mg
50 mg
100 mg
500 mg
1 g
$100.00
$230.00
$450.00
$1715.00
$2900.00
4
(0)

Vinblastine binds to tubulin and disrupts microtubule assembly, which could inhibit ciliary protein expression.

Colchicine

64-86-8sc-203005
sc-203005A
sc-203005B
sc-203005C
sc-203005D
sc-203005E
1 g
5 g
50 g
100 g
500 g
1 kg
$98.00
$315.00
$2244.00
$4396.00
$17850.00
$34068.00
3
(2)

Colchicine binds to tubulin, preventing microtubule polymerization, which may inhibit ciliary protein assembly and expression.

Nocodazole

31430-18-9sc-3518B
sc-3518
sc-3518C
sc-3518A
5 mg
10 mg
25 mg
50 mg
$58.00
$83.00
$140.00
$242.00
38
(2)

Nocodazole disrupts microtubule polymerization and could lead to reduced expression of proteins required for cilia structure.