TERT Activators
The term TERT activators refers to a class of chemicals that modulate the activity of telomerase reverse transcriptase (TERT), a key component of the telomerase enzyme responsible for maintaining telomere length in cells. While direct activators of TERT may not be readily identified, these chemicals target pathways and cellular processes associated with TERT expression and function. Resveratrol, a polyphenolic compound, activates AMPK, a central regulator of cellular energy homeostasis. The activation of AMPK by resveratrol may indirectly impact TERT by influencing downstream signaling pathways associated with AMPK, providing a link between cellular energy status and TERT activity. Rapamycin, an mTOR inhibitor, can impact TERT through the mTOR signaling pathway. Its inhibition of mTOR may affect downstream cascades involved in cellular growth and longevity, providing a link between mTOR signaling and TERT activity.
N-acetylcysteine (NAC), a precursor of glutathione with antioxidant properties, may influence TERT through modulation of oxidative stress pathways. Its effects on cellular responses to oxidative stress could indirectly impact TERT expression or activity, suggesting a connection between oxidative stress and TERT regulation. Curcumin, a polyphenolic compound with antioxidant and anti-inflammatory properties, may influence TERT through modulation of signaling pathways associated with oxidative stress and inflammation. Its effects on cellular responses could indirectly affect TERT expression or activity, indicating a link between inflammation and TERT regulation. 3,3'-Diindolylmethane (DIM), found in cruciferous vegetables, may influence TERT through modulation of multiple signaling pathways, including those related to inflammation and cellular survival. Its effects on cellular responses could indirectly impact TERT expression or activity, suggesting a role for inflammation and cellular survival pathways in TERT regulation. In summary, the chemical class of TERT activators encompasses compounds that, while not directly activating TERT, modulate its expression and function through various signaling pathways.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
A polyphenolic compound that activates AMP-activated protein kinase (AMPK), which may indirectly impact TERT through regulation of cellular energy homeostasis and modulation of downstream pathways associated with AMPK signaling. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase (HDAC) inhibitor that can influence chromatin structure and gene expression. Trichostatin A may affect TERT expression through epigenetic modifications, potentially leading to increased transcription of the TERT gene. | ||||||
Dihydro Artemisinin | 71939-50-9 | sc-211332 | 100 mg | $233.00 | 1 | |
A derivative of artemisinin with anti-malarial properties. Dihydroartemisinin may impact TERT through modulation of oxidative stress pathways, influencing cellular responses that could indirectly affect TERT expression or activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor that can influence TERT through the mTOR signaling pathway. Rapamycin's inhibition of mTOR may impact downstream cascades involved in cellular growth and longevity, potentially affecting TERT expression or activity. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
A flavonoid with antioxidant properties that may influence TERT through modulation of pathways associated with oxidative stress. Quercetin's effects on cellular responses to oxidative stress could indirectly impact TERT expression or activity. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
A short-chain fatty acid and HDAC inhibitor that can influence TERT through epigenetic modifications. Sodium butyrate may impact chromatin structure and gene expression, potentially leading to increased transcription of the TERT gene. | ||||||
Thymoquinone | 490-91-5 | sc-215986 sc-215986A | 1 g 5 g | $47.00 $133.00 | 21 | |
A bioactive compound found in Nigella sativa that may influence TERT through modulation of various signaling pathways, including those related to oxidative stress and inflammation. Thymoquinone's effects on cellular responses could indirectly affect TERT expression or activity. | ||||||
NDGA (Nordihydroguaiaretic acid) | 500-38-9 | sc-200487 sc-200487A sc-200487B | 1 g 5 g 25 g | $109.00 $384.00 $2190.00 | 3 | |
A natural phenolic compound with antioxidant properties that may influence TERT through modulation of oxidative stress pathways. NDGA's effects on cellular responses to oxidative stress could indirectly impact TERT expression or activity. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
A precursor of glutathione with antioxidant properties that may influence TERT through modulation of oxidative stress pathways. NAC's effects on cellular responses to oxidative stress could indirectly impact TERT expression or activity. | ||||||
3,3′-Diindolylmethane | 1968-05-4 | sc-204624 sc-204624A sc-204624B sc-204624C sc-204624D sc-204624E | 100 mg 500 mg 5 g 10 g 50 g 1 g | $37.00 $65.00 $89.00 $421.00 $681.00 $66.00 | 8 | |
A compound found in cruciferous vegetables that may influence TERT through modulation of multiple signaling pathways, including those related to inflammation and cellular survival. DIM's effects on cellular responses could indirectly impact TERT expression or activity. | ||||||