TDP1 Activators
The class of TDP1 Activators is not well-defined, given that the direct activators of TDP1 are not well established. However, ATP, Magnesium ions, Zinc ions, and NAD+ can be considered in this context.
ATP, or Adenosine Triphosphate, is a molecule that provides the energy necessary for many cellular processes, including DNA repair mechanisms involving TDP1. Magnesium and Zinc ions, although not typically referred to as activators in the classic sense, are essential for the activation of many enzymes, including TDP1. NAD+ is involved in DNA repair processes, potentially influencing the function of enzymes like TDP1. Several other compounds, like dGTP, dATP, dCTP, dTTP, and certain DNA-damaging agents like H2O2, Ethidium Bromide, Formaldehyde, and Acetaldehyde, might also indirectly influence TDP1 activity. They can cause DNA damage, increasing the need for DNA repair mechanisms involving TDP1. Despite the critical role of these molecules in the function of TDP1, they are not typically referred to as activators in the classic sense of directly increasing the activity of TDP1.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc ions are required for the structural integrity of many DNA repair enzymes, including TDP1. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $56.00 $186.00 $296.00 $655.00 $2550.00 $3500.00 $10500.00 | 4 | |
NAD+ is involved in DNA repair processes, potentially influencing the function of enzymes like TDP1. | ||||||
2′-Deoxyguanosine-13C10,15N5 | 961-07-9 (unlabeled) | sc-500624 | 1 mg | $700.00 | ||
dGTP is involved in the DNA repair process and may indirectly influence TDP1 activity. | ||||||
Thymidine | 50-89-5 | sc-296542 sc-296542A sc-296542C sc-296542D sc-296542E sc-296542B | 1 g 5 g 100 g 250 g 1 kg 25 g | $48.00 $72.00 $265.00 $449.00 $1724.00 $112.00 | 16 | |
dTTP is a nucleotide involved in DNA synthesis and repair, potentially influencing TDP1. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $30.00 $60.00 $93.00 | 27 | |
H2O2 can induce oxidative stress, potentially increasing the need for DNA repair mechanisms involving TDP1. | ||||||
Ethidium bromide | 1239-45-8 | sc-203735 sc-203735A sc-203735B sc-203735C | 1 g 5 g 25 g 100 g | $47.00 $147.00 $576.00 $2045.00 | 12 | |
Ethidium bromide intercalates into DNA, causing damage that may necessitate repair mechanisms involving TDP1. | ||||||
FCM Fixation buffer (10X) | sc-3622 | 10 ml @ 10X | $61.00 | 16 | ||
Formaldehyde can cause DNA cross-linking and damage, potentially requiring DNA repair mechanisms involving TDP1. | ||||||