TCEA1 Inhibitors
TCEA1 inhibitors belong to a distinct chemical class that has garnered attention for their role in modulating specific cellular processes. These inhibitors are designed to target and interact with the Transcription Elongation Factor A1 (TCEA1), a crucial protein involved in transcriptional regulation within cells. TCEA1 plays a significant role in the transcription elongation process by facilitating the movement of RNA polymerase along the DNA template, ultimately leading to the successful synthesis of RNA molecules.
Inhibiting TCEA1 is believed to exert an influence on gene expression, as the protein's activity is intricately linked to the regulation of transcriptional elongation rates. The chemical entities classified as TCEA1 inhibitors are characterized by their distinct molecular structures, which enable them to bind to TCEA1 in a specific manner. This interaction can result in the modulation of transcription dynamics and impact various cellular pathways. Research into TCEA1 inhibitors is ongoing, exploring their mechanisms of action and to unveil novel insights into gene expression regulation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Actinomycin D inhibits TCEA1 by intercalating into DNA and preventing RNA synthesis by RNA polymerase. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
Rifampicin inhibits TCEA1 by binding to bacterial RNA polymerase and preventing transcription initiation. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
α-Amanitin inhibits TCEA1 by binding to RNA polymerase II and blocking transcription elongation, leading to RNA synthesis disruption. | ||||||
Thiolutin | 87-11-6 | sc-200387 sc-200387A | 1 mg 5 mg | $101.00 $406.00 | 1 | |
Thiolutin inhibits TCEA1 by binding to RNA polymerase and inhibiting transcription elongation through steric hindrance. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $101.00 | 5 | |
Cordycepin inhibits TCEA1 by being incorporated into nascent RNA during transcription, leading to premature termination. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Triptolide inhibits TCEA1 by binding to RNA polymerase and suppressing transcription initiation and elongation. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $43.00 $189.00 $316.00 $663.00 | 6 | |
5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole inhibits TCEA1 by preventing RNA elongation by RNA polymerase II. | ||||||