TAT1 Activators
TAT1 Activators pertain to a collection of chemical compounds specifically identified or designed to enhance or stimulate the activity of TAT1, commonly recognized as tyrosine aminotransferase. This enzyme plays a central role in the metabolic degradation of the amino acid tyrosine, catalyzing its conversion to p-hydroxyphenylpyruvate. The significance of this reaction is rooted in amino acid metabolism, which is crucial for maintaining cellular health, energy balance, and the synthesis of essential molecules.
The mode of action of TAT1 activators can be diverse. Some of these chemical agents might bind directly to the TAT1 enzyme, prompting a conformational change that renders its active site more accessible or augmenting its affinity for the tyrosine substrate. Alternatively, certain activators might function indirectly by modulating cellular pathways or conditions that intersect with TAT1's activity. For instance, agents that enhance the availability of co-factors or co-enzymes essential for TAT1's enzymatic function could serve as indirect activators. On another note, some chemicals might work by shielding TAT1 from inhibitory molecules or factors that decrease its stability, ensuring that the enzyme remains active for more extended periods within the cell. Furthermore, given the dynamic environment within cells, factors like pH, ionic strength, and the presence of specific metal ions can all play a part in modulating the enzyme's activity. Chemicals that optimize these conditions could thus act as TAT1 activators. Understanding the intricacies of TAT1 activators provides a comprehensive perspective into the nuances of tyrosine metabolism and enzymology. Given the foundational role of enzymes in cellular biochemistry, dissecting the impact and function of chemicals that modulate their activity offers profound insights into cellular processes and metabolic pathways.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
L-Tyrosine | 60-18-4 | sc-473512 sc-473512A sc-473512B sc-473512C | 100 g 250 g 1 kg 5 kg | $52.00 $213.00 $1670.00 $8328.00 | 1 | |
Acts as the primary substrate for TAT1, initiating the activation process by binding to the enzyme's active site and triggering conformational changes for catalytic activity. | ||||||
3,4-Dihydroxy-DL-phenylalanine | 63-84-3 | sc-256584 sc-256584A sc-256584B | 1 g 5 g 25 g | $21.00 $37.00 $188.00 | ||
Functions as an analog of tyrosine, facilitating TAT1 activation by structurally resembling the substrate, thereby enhancing its binding affinity to the enzyme. | ||||||
L-Phenylalanine | 63-91-2 | sc-394058 sc-394058A sc-394058B | 100 g 500 g 1 kg | $114.00 $466.00 $693.00 | 1 | |
Serves as a precursor to tyrosine in metabolic pathways, indirectly contributing to TAT1 activation by providing a substrate for tyrosine synthesis. | ||||||
N-Methyl-DL-tyrosine hydrochloride | 19897-63-3 | sc-470613 | 1 g | $33.00 | ||
Modifies the tyrosine structure, potentially enhancing TAT1 activation by promoting favorable interactions with the enzyme's active site. | ||||||
3-Fluoro-DL-tyrosine | 403-90-7 | sc-266661 | 100 mg | $67.00 | ||
Alters the chemical properties of tyrosine through halogenation, likely influencing TAT1 activation by introducing changes in substrate recognition and binding. | ||||||
Levodopa | 59-92-7 | sc-205372 sc-205372A | 5 g 25 g | $54.00 $171.00 | 9 | |
Associated with tyrosine metabolism, potentially participating in TAT1 activation pathways by serving as a metabolic precursor for activated tyrosine substrates. | ||||||
O-Methyl-D-Tyrosine | 39878-65-4 | sc-269982 sc-269982A | 1 g 5 g | $74.00 $302.00 | ||
Introduces methylation modifications to tyrosine, potentially enhancing TAT1 activation by altering substrate's chemical properties for increased enzymatic activity. | ||||||
L-Tyrosine Ethyl ester | 949-67-7 | sc-295341 sc-295341A | 5 g 25 g | $64.00 $205.00 | ||
Modifies tyrosine through ethylation, potentially influencing TAT1 activation by introducing structural changes that enhance substrate-enzyme interactions. | ||||||
3-Chloro-L-tyrosine | 7423-93-0 | sc-231624 | 1 g | $77.00 | ||
Introduces chlorination modifications to tyrosine, potentially influencing TAT1 activation by altering substrate structure and enhancing binding affinity to the enzyme. | ||||||
3-Iodo-L-tyrosine | 70-78-0 | sc-216471 sc-216471A sc-216471B | 1 g 5 g 25 g | $80.00 $200.00 $592.00 | ||
Induces iodination modifications in tyrosine, likely influencing TAT1 activation by introducing structural changes that facilitate substrate recognition and binding. | ||||||