T2R49 Activators
T2R49 Activators consists of various bitter compounds known to activate members of the T2R family of bitter taste receptors, which likely includes T2R49. These receptors are G protein-coupled receptors (GPCRs) that play a crucial role in the detection of bitter-tasting compounds. The activation of these receptors is key in the perception of bitterness, an important mechanism for the avoidance of harmful substances.
Compounds like Phenylthiocarbamide (PTC) and Propylthiouracil (PROP) are well-known for their ability to activate bitter taste receptors and are often used in genetic studies related to taste perception. Quinine, a classic bitter compound found in tonic water, and Denatonium, recognized as one of the most bitter substances, are likely activators of T2R49. Similarly, naturally occurring bitter compounds such as Aloin, Caffeine, and Absinthin are activators of T2R49 due to their inherent bitterness.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
N-Phenylthiourea | 103-85-5 | sc-236086 | 100 g | $319.00 | ||
PTC is a well-known compound that activates certain bitter taste receptors, potentially including T2R49. | ||||||
Quinine | 130-95-0 | sc-212616 sc-212616A sc-212616B sc-212616C sc-212616D | 1 g 5 g 10 g 25 g 50 g | $79.00 $104.00 $166.00 $354.00 $572.00 | 1 | |
Quinine, a compound found in tonic water, is a classic bitter compound that may activate T2R49. | ||||||
Denatonium benzoate | 3734-33-6 | sc-234525 sc-234525A sc-234525B sc-234525C sc-234525D | 1 g 5 g 25 g 100 g 250 g | $32.00 $47.00 $141.00 $473.00 $921.00 | ||
Denatonium is one of the most bitter substances known and may interact with T2R49. | ||||||
6-Propyl-2-thiouracil | 51-52-5 | sc-214383 sc-214383A sc-214383B sc-214383C | 10 g 25 g 100 g 1 kg | $37.00 $56.00 $224.00 $1997.00 | ||
PROP is structurally similar to PTC and known to activate bitter taste receptors. | ||||||
Aloin | 1415-73-2 | sc-214525 sc-214525A | 25 mg 100 mg | $159.00 $271.00 | 1 | |
Aloin, a compound in aloe, is bitter and may activate bitter taste receptors like T2R49. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine, a bitter compound in coffee and tea, may interact with T2R49. | ||||||
Saccharin | 81-07-2 | sc-212902 sc-212902A sc-212902B | 100 mg 1 g 10 g | $173.00 $235.00 $286.00 | ||
Saccharin is an artificial sweetener with a bitter aftertaste that may activate T2R49. | ||||||
D-(−)-Salicin | 138-52-3 | sc-218004 | 5 g | $59.00 | ||
Salicin, a bitter compound in willow bark, might activate T2R49. | ||||||
Naringin | 10236-47-2 | sc-203443 sc-203443A | 25 g 50 g | $45.00 $101.00 | 7 | |
Naringin, a bitter flavonoid in grapefruits, may activate T2R49. | ||||||