Subh2bv Inhibitors
Subh2bv inhibitors are a class of chemical compounds that specifically target and inhibit the activity of Subh2bv, a histone variant involved in chromatin remodeling and gene regulation. Histones are proteins that package and organize DNA into chromatin, and modifications to histones, including the incorporation of variants like Subh2bv, can significantly influence chromatin structure and gene expression. Subh2bv is thought to play a role in the dynamic regulation of chromatin, possibly participating in processes such as DNA repair, replication, or transcriptional regulation. Inhibitors of Subh2bv are designed to disrupt its function, thereby altering the chromatin landscape and potentially affecting the accessibility of DNA to various transcriptional machinery or regulatory proteins.
The mechanism of action of Subh2bv inhibitors typically involves binding to the protein in such a way that it interferes with its integration into nucleosomes or its ability to interact with other chromatin-associated factors. Some inhibitors may compete with endogenous substrates that bind to Subh2bv, while others might induce conformational changes that prevent its proper function within chromatin. By inhibiting Subh2bv, these compounds disrupt the normal modifications or rearrangements of chromatin, which can lead to changes in gene expression patterns. This inhibition can have downstream effects on a variety of cellular processes, as chromatin structure plays a fundamental role in regulating access to genetic information. Research into Subh2bv inhibitors provides valuable insights into the role of histone variants in epigenetic regulation and chromatin dynamics, helping to elucidate the complex molecular mechanisms governing gene regulation and genome stability. Understanding how Subh2bv contributes to these processes is crucial for exploring how cells control gene expression and respond to environmental and developmental cues.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A inhibits H2B.L histone variant 1 expression by blocking histone deacetylase activity, leading to increased histone acetylation and subsequent chromatin remodeling that may impede transcription of the gene encoding H2B.L. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Vorinostat inhibits H2B.L histone variant 1 expression by targeting histone deacetylase enzymes, resulting in hyperacetylation of histones and altered chromatin structure, which can interfere with the transcriptional machinery at the gene locus. | ||||||
Romidepsin | 128517-07-7 | sc-364603 sc-364603A | 1 mg 5 mg | $214.00 $622.00 | 1 | |
Romidepsin suppresses H2B.L histone variant 1 expression by inhibiting histone deacetylase activity, leading to accumulation of acetylated histones and subsequent chromatin remodeling, which may hinder transcription of the gene encoding H2B.L. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate inhibits H2B.L histone variant 1 expression by serving as a histone deacetylase inhibitor, leading to increased histone acetylation and chromatin remodeling that may impede transcriptional activation of the gene encoding H2B.L. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
Entinostat suppresses H2B.L histone variant 1 expression by targeting histone deacetylase enzymes, resulting in hyperacetylation of histones and altered chromatin structure, which can interfere with the transcriptional machinery at the gene locus. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $196.00 | 9 | |
Panobinostat inhibits H2B.L histone variant 1 expression by blocking histone deacetylase activity, leading to increased histone acetylation and subsequent chromatin remodeling that may impede transcription of the gene encoding H2B.L. | ||||||
Belinostat | 414864-00-9 | sc-269851 sc-269851A | 10 mg 100 mg | $153.00 $561.00 | ||
Belinostat suppresses H2B.L histone variant 1 expression by inhibiting histone deacetylase enzymes, resulting in hyperacetylation of histones and altered chromatin structure, which can interfere with the transcriptional machinery at the gene locus. | ||||||
Scriptaid | 287383-59-9 | sc-202807 sc-202807A | 1 mg 5 mg | $63.00 $179.00 | 11 | |
Scriptaid suppresses H2B.L histone variant 1 expression by inhibiting histone deacetylase enzymes, resulting in hyperacetylation of histones and altered chromatin structure, which can interfere with the transcriptional machinery at the gene locus. | ||||||
M 344 | 251456-60-7 | sc-203124 sc-203124A | 1 mg 5 mg | $107.00 $316.00 | 8 | |
M344 inhibits H2B.L histone variant 1 expression by blocking histone deacetylase activity, leading to increased histone acetylation and subsequent chromatin remodeling that may impede transcription of the gene encoding H2B.L. | ||||||
PI3K/HDAC Inhibitor | 1339928-25-4 | sc-364584 sc-364584A | 5 mg 10 mg | $340.00 $462.00 | ||
RGFP966 suppresses H2B.L histone variant 1 expression by inhibiting histone deacetylase enzymes, resulting in hyperacetylation of histones and altered chromatin structure, which can interfere with the transcriptional machinery at the gene locus. | ||||||