STELLA Inhibitors
STELLA Inhibitors include compounds that influence cellular signaling pathways and epigenetic states to inhibit the function of STELLA. These chemicals do not directly target STELLA but rather modulate various biochemical and cellular pathways, creating conditions that may hinder the role of STELLA.
These inhibitors work through diverse mechanisms. Epigenetic modifiers like 5-Aza-2'-deoxycytidine and DZNep can disrupt the epigenetic landscape crucial for maintaining pluripotency, affecting STELLA's function. Similarly, compounds that influence gene expression and chromatin state, such as Mithramycin A and BIX-01294, can indirectly inhibit the role of STELLA in pluripotency maintenance. Other chemicals, like PD0332991 (a CDK4/6 inhibitor) and Nicotinamide, affect cell cycle dynamics and cellular metabolism, respectively, which can disrupt the cellular state necessary for maintaining pluripotency. Compounds like Kenpaullone and Rapamycin, through their influence on signaling pathways such as Wnt and mTOR, can alter the balance of signals required for pluripotency, thereby inhibiting STELLA's function.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
A DNA methyltransferase inhibitor that can alter epigenetic marks and potentially disrupt the expression patterns of genes associated with pluripotency, thereby inhibiting STELLA's function. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
An antitumor antibiotic that binds to DNA and affects gene transcription. It can potentially disrupt the expression of pluripotency-related genes, thereby inhibiting STELLA's activity. | ||||||
Histone Lysine Methyltransferase Inhibitor Inhibitor | 935693-62-2 (free base) | sc-202651 | 5 mg | $151.00 | 4 | |
A G9a histone methyltransferase inhibitor, potentially disrupting the epigenetic state necessary for maintaining pluripotency, thereby affecting STELLA's function. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $131.00 $515.00 | 2 | |
A DNA methyltransferase inhibitor that does not cause DNA damage. It can potentially alter the epigenetic landscape, affecting STELLA's role in pluripotency. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
A histone deacetylase inhibitor, which could disrupt the chromatin state necessary for maintaining pluripotency, thereby inhibiting STELLA's function. | ||||||
Palbociclib | 571190-30-2 | sc-507366 | 50 mg | $321.00 | ||
A CDK4/6 inhibitor that can alter cell cycle progression, potentially disrupting the cellular state required for maintaining pluripotency and inhibiting STELLA. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $44.00 $66.00 $204.00 $831.00 | 6 | |
A form of vitamin B3 that can influence sirtuin activity and cellular metabolism, potentially disrupting the state necessary for pluripotency and inhibiting STELLA. | ||||||
Kenpaullone | 142273-20-9 | sc-200643 sc-200643A sc-200643B sc-200643C | 1 mg 5 mg 10 mg 25 mg | $61.00 $153.00 $231.00 $505.00 | 1 | |
An inhibitor of glycogen synthase kinase-3 (GSK-3), which can influence Wnt signaling and cellular differentiation pathways, potentially inhibiting STELLA's function. | ||||||
Levonorgestrel | 797-63-7 | sc-205731 sc-205731A | 100 mg 500 mg | $44.00 $198.00 | 1 | |
A synthetic progestin that can influence hormonal signaling pathways, potentially affecting the cellular environment and inhibiting STELLA's role in germ cell development. | ||||||