STELLA Activators
The class of chemicals known as STELLA Activators includes compounds that potentially influence the cellular environment and signaling pathways to support the function of STELLA in maintaining pluripotency and regulating germ cell development. These chemicals do not directly activate STELLA but modulate various biochemical and cellular pathways, creating conditions that may favor the role of STELLA.
The mechanisms of action of these chemicals are varied. For example, epigenetic modifiers like 5-Azacytidine and Sodium butyrate can change the chromatin landscape, potentially influencing the expression of genes associated with pluripotency and germ cell development, thereby supporting STELLA's function. Compounds like Retinoic acid and Vitamin C influence differentiation and epigenetic states, respectively, and could create an environment conducive to the roles played by STELLA in cellular processes. Similarly, inhibitors of signaling pathways like PD0325901 (MEK inhibitor), Rapamycin (mTOR inhibitor), and LY294002 (PI3K inhibitor) can alter cell fate decisions and growth signals, indirectly affecting the cellular context in which STELLA operates. By modulating these pathways, these chemicals can indirectly support STELLA's role in maintaining pluripotency and regulating germ cell development.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
An epigenetic modifier that inhibits DNA methyltransferases, potentially leading to demethylation of pluripotency genes, indirectly supporting STELLA's role in pluripotency maintenance. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
A histone deacetylase inhibitor that can alter chromatin structure, potentially influencing gene expression patterns related to pluripotency and impacting STELLA activity. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $46.00 | 5 | |
An antioxidant known to influence epigenetic modifications and enhance the efficiency of iPSC generation, potentially supporting STELLA's role in pluripotency. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor that can change gene expression patterns, possibly influencing STELLA's function in germ cell development. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylyl cyclase and raises cAMP levels, potentially influencing signaling pathways associated with pluripotency and germ cell development, indirectly impacting STELLA. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor that can influence cellular growth and proliferation signals, potentially impacting STELLA's role in pluripotency and germ cell development. | ||||||
A 83-01 | 909910-43-6 | sc-203791 sc-203791A | 10 mg 50 mg | $202.00 $811.00 | 16 | |
A TGF-β receptor inhibitor that can influence cellular signaling pathways associated with differentiation, indirectly affecting STELLA's function. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
A ROCK inhibitor that affects cytoskeletal dynamics and cell survival, potentially influencing pluripotency-related pathways and STELLA's activity. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
Inhibits TGF-β signaling, potentially affecting cellular differentiation processes and indirectly impacting STELLA's function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor that affects AKT signaling, potentially influencing cellular processes related to pluripotency and germ cell development, impacting STELLA. | ||||||