SRE-ZBP Inhibitors
SRE-ZBP inhibitors, as outlined here, encompass a broad range of chemicals that target RNA synthesis, gene transcription, and RNA splicing. These compounds act on various stages of RNA processing and transcription, aiming to indirectly influence SRE-ZBP function. For instance, Actinomycin D, α-amanitin, DRB, and Triptolide all target the RNA polymerase II machinery, which is crucial for RNA synthesis and gene transcription. By disrupting this machinery, they can influence the gene expression mechanisms potentially associated with SRE-ZBP.
On the other hand, a significant portion of the list, including Spliceostatin A, Pladienolide B, Isoginkgetin, Meayamycin, Sudemycin E, E7107, SSA, and Herboxidiene, specifically targets the RNA splicing mechanism. These compounds bind to or modulate the function of the SF3b complex or related entities. This targeted approach to splicing interference can substantially modulate RNA processing pathways in which SRE-ZBP could be involved.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Interferes with RNA synthesis by binding DNA; can impact gene expression mechanisms tied to SRE-ZBP. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
Inhibits RNA polymerase II; this inhibition can affect gene transcription related to SRE-ZBP. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $43.00 $189.00 $316.00 $663.00 | 6 | |
Inhibits RNA polymerase II; can influence transcription processes involving SRE-ZBP. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Inhibits RNA polymerase II; can impact transcription mechanisms potentially related to SRE-ZBP. | ||||||
Spliceostatin A | 391611-36-2 | sc-507481 | 1 mg | $1800.00 | ||
Binds splicing factor SF3b and inhibits splicing; can affect RNA processing pathways involving SRE-ZBP. | ||||||
Pladienolide B | 445493-23-2 | sc-391691 sc-391691B sc-391691A sc-391691C sc-391691D sc-391691E | 0.5 mg 10 mg 20 mg 50 mg 100 mg 5 mg | $299.00 $5699.00 $11099.00 $25500.00 $66300.00 $2875.00 | 63 | |
Targets SF3b complex, altering splicing; can influence RNA splicing pathways tied to SRE-ZBP. | ||||||
Isoginkgetin | 548-19-6 | sc-507430 | 5 mg | $225.00 | ||
Splicing inhibitor; can modulate RNA splicing and potentially impact SRE-ZBP functions. | ||||||
Herboxidiene | 142861-00-5 | sc-506378 | 1 mg | $1009.00 | ||
Binds SF3b complex and inhibits splicing; can influence RNA splicing pathways involving SRE-ZBP. | ||||||