Date published: 2026-6-1

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SphK Substrates

Santa Cruz Biotechnology now offers a broad range of SphK Substrates for use in various applications. Sphingosine kinases (SphKs) are enzymes that play a crucial role in the sphingolipid metabolic pathway, converting sphingosine to sphingosine-1-phosphate (S1P), a signaling molecule involved in various cellular processes. SphK substrates are essential in biochemical research as they enable scientists to study the activity and regulation of SphKs, contributing to a deeper understanding of cellular signaling pathways. These substrates are particularly valuable in studies exploring cellular functions such as proliferation, differentiation, and apoptosis. Researchers often utilize SphK substrates in in vitro assays to investigate enzyme kinetics, identify inhibitors or activators, and understand the molecular mechanisms underlying SphK-related pathways. Additionally, these substrates can be used in the development of biosensors for detecting sphingosine and related metabolites, thereby advancing research in bioanalytical chemistry. The availability of high-quality SphK substrates supports the scientific community in explaining the complex roles of sphingolipids in cellular biology and offers tools for the development of new technologies and methodologies. View detailed information on our available SphK Substrates by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Dihydro-D-erythro-Sphingosine

764-22-7sc-203911
10 mg
$77.00
(0)

Dihydro-D-erythro-Sphingosine serves as a substrate for sphingosine kinases, playing a crucial role in sphingolipid metabolism. Its unique structural conformation allows for effective binding to the enzyme, promoting the formation of sphingosine-1-phosphate. This compound exhibits distinct hydrophilic and hydrophobic regions, influencing membrane fluidity and cellular signaling. Additionally, its reactivity with various lipid components can modulate cellular stress responses and apoptosis pathways.