SKI-1 Activators
The chemical class of SKI-1 Activators encompasses a variety of compounds that can potentially stimulate or modulate the activity of SKI-1, a protease involved in the regulation of lipid metabolism and stress response. This class includes several statins, like Lovastatin, Simvastatin, Rosuvastatin, and Atorvastatin, which can influence cholesterol biosynthesis pathways, potentially leading to the indirect activation of SKI-1 through the processing of SREBPs.
Additionally, compounds like Mevalonic Acid and 25-Hydroxycholesterol, involved in cholesterol metabolism, can impact the regulation of SKI-1. PPAR agonists, such as Pioglitazone and Fenofibrate, and AMPK activators like Metformin, AICAR, and Berberine, are included due to their role in modulating lipid metabolism, potentially affecting SKI-1. Oleic Acid, as a fatty acid, could also influence lipid metabolic pathways, potentially impacting SKI-1 activity.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lovastatin | 75330-75-5 | sc-200850 sc-200850A sc-200850B | 5 mg 25 mg 100 mg | $28.00 $88.00 $332.00 | 12 | |
As a statin, Lovastatin can influence cholesterol synthesis pathways, potentially leading to the indirect activation of SKI-1 by affecting SREBP (Sterol Regulatory Element-Binding Proteins) processing. | ||||||
Simvastatin | 79902-63-9 | sc-200829 sc-200829A sc-200829B sc-200829C | 50 mg 250 mg 1 g 5 g | $30.00 $87.00 $132.00 $434.00 | 13 | |
Similar to Lovastatin, Simvastatin impacts cholesterol biosynthesis, which could indirectly enhance SKI-1 activity via SREBP processing. | ||||||
Rosuvastatin | 287714-41-4 | sc-481834 | 10 mg | $142.00 | 8 | |
Another statin that can affect cholesterol metabolism, potentially leading to indirect activation of SKI-1 through SREBP pathways. | ||||||
Atorvastatin | 134523-00-5 | sc-337542A sc-337542 | 50 mg 100 mg | $252.00 $495.00 | 9 | |
A statin that influences cholesterol biosynthesis pathways, potentially affecting SKI-1 activity indirectly. | ||||||
25-Hydroxycholesterol | 2140-46-7 | sc-214091B sc-214091 sc-214091A sc-214091C | 5 mg 10 mg 25 mg 100 mg | $52.00 $89.00 $166.00 $465.00 | 8 | |
As an oxysterol, it can regulate lipid homeostasis and potentially affect SKI-1 activity via SREBP pathways. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
A PPAR-gamma agonist known to influence lipid metabolism and might indirectly affect SKI-1 activity. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $42.00 $62.00 $153.00 $255.00 $500.00 $30.00 | 37 | |
An AMP-activated protein kinase (AMPK) activator that influences metabolic pathways, potentially affecting SKI-1 activity. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
An AMPK activator that can influence cellular metabolism, potentially leading to the indirect activation of SKI-1. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $40.00 | 9 | |
A PPAR-alpha agonist that modulates lipid metabolism and could indirectly influence SKI-1 activity. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $90.00 | 1 | |
Known to activate AMPK and influence lipid metabolism, potentially affecting SKI-1 activity. | ||||||