Date published: 2026-1-9

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SGSM CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. SGSM gene silencers are available as SGSM CRISPR/Cas9 Knockout plasmids and SGSM Double Nickase Plasmids. SGSM CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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SGSM CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SGSM1 CRISPR/Cas9 KO Plasmid (h)

sc-414345hGene KnockoutGFP0
(0)

SGSM1 HDR Plasmid (h)

sc-414345-HDRhHomology Directed RepairPuromycin0
(0)

SGSM1 Double Nickase Plasmid (h)

sc-414345-NIChGene KnockoutPuromycin0
(0)

SGSM1 Double Nickase Plasmid (h2)

sc-414345-NIC-2hGene KnockoutPuromycin0
(0)

SGSM1 CRISPR/Cas9 KO Plasmid (m)

sc-424665mGene KnockoutGFP0
(0)

SGSM1 HDR Plasmid (m)

sc-424665-HDRmHomology Directed RepairPuromycin0
(0)

SGSM1 Double Nickase Plasmid (m)

sc-424665-NICmGene KnockoutPuromycin0
(0)

SGSM1 Double Nickase Plasmid (m2)

sc-424665-NIC-2mGene KnockoutPuromycin0
(0)

SGSM2 CRISPR/Cas9 KO Plasmid (h)

sc-411382hGene KnockoutGFP0
(0)

SGSM2 HDR Plasmid (h)

sc-411382-HDRhHomology Directed RepairPuromycin0
(0)

SGSM2 Double Nickase Plasmid (h)

sc-411382-NIChGene KnockoutPuromycin0
(0)

SGSM2 Double Nickase Plasmid (h2)

sc-411382-NIC-2hGene KnockoutPuromycin0
(0)

SGSM2 CRISPR/Cas9 KO Plasmid (m)

sc-430185mGene KnockoutGFP0
(0)

SGSM2 HDR Plasmid (m)

sc-430185-HDRmHomology Directed RepairPuromycin0
(0)

SGSM2 Double Nickase Plasmid (m)

sc-430185-NICmGene KnockoutPuromycin0
(0)

SGSM2 Double Nickase Plasmid (m2)

sc-430185-NIC-2mGene KnockoutPuromycin0
(0)

SGSM3 CRISPR/Cas9 KO Plasmid (h)

sc-411999hGene KnockoutGFP0
(0)

SGSM3 HDR Plasmid (h)

sc-411999-HDRhHomology Directed RepairPuromycin0
(0)

SGSM3 Double Nickase Plasmid (h)

sc-411999-NIChGene KnockoutPuromycin0
(0)

SGSM3 Double Nickase Plasmid (h2)

sc-411999-NIC-2hGene KnockoutPuromycin0
(0)

SGSM3 CRISPR/Cas9 KO Plasmid (m)

sc-430621mGene KnockoutGFP0
(0)

SGSM3 HDR Plasmid (m)

sc-430621-HDRmHomology Directed RepairPuromycin0
(0)

SGSM3 Double Nickase Plasmid (m)

sc-430621-NICmGene KnockoutPuromycin0
(0)

SGSM3 Double Nickase Plasmid (m2)

sc-430621-NIC-2mGene KnockoutPuromycin0
(0)

SGSM CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SGSM1 CRISPR Activation Plasmid (h)

sc-414345-ACThGene ActivationPuro, Blast, Hygro0
(0)

SGSM1 CRISPR Activation Plasmid (h2)

sc-414345-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SGSM1 Lentiviral Activation Particles (h)

sc-414345-LAChGene ActivationPuro, Blast, Hygro0
(0)

SGSM1 Lentiviral Activation Particles (h2)

sc-414345-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SGSM1 CRISPR Activation Plasmid (m)

sc-424665-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SGSM1 CRISPR Activation Plasmid (m2)

sc-424665-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SGSM1 Lentiviral Activation Particles (m)

sc-424665-LACmGene ActivationPuro, Blast, Hygro0
(0)

SGSM1 Lentiviral Activation Particles (m2)

sc-424665-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SGSM2 CRISPR Activation Plasmid (h)

sc-411382-ACThGene ActivationPuro, Blast, Hygro0
(0)

SGSM2 CRISPR Activation Plasmid (h2)

sc-411382-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SGSM2 Lentiviral Activation Particles (h)

sc-411382-LAChGene ActivationPuro, Blast, Hygro0
(0)

SGSM2 Lentiviral Activation Particles (h2)

sc-411382-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SGSM2 CRISPR Activation Plasmid (m)

sc-430185-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SGSM2 CRISPR Activation Plasmid (m2)

sc-430185-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SGSM2 Lentiviral Activation Particles (m)

sc-430185-LACmGene ActivationPuro, Blast, Hygro0
(0)

SGSM2 Lentiviral Activation Particles (m2)

sc-430185-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SGSM3 CRISPR Activation Plasmid (h)

sc-411999-ACThGene ActivationPuro, Blast, Hygro0
(0)

SGSM3 CRISPR Activation Plasmid (h2)

sc-411999-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SGSM3 Lentiviral Activation Particles (h)

sc-411999-LAChGene ActivationPuro, Blast, Hygro0
(0)

SGSM3 Lentiviral Activation Particles (h2)

sc-411999-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SGSM3 CRISPR Activation Plasmid (m)

sc-430621-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SGSM3 CRISPR Activation Plasmid (m2)

sc-430621-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SGSM3 Lentiviral Activation Particles (m)

sc-430621-LACmGene ActivationPuro, Blast, Hygro0
(0)

SGSM3 Lentiviral Activation Particles (m2)

sc-430621-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)