SAP 145 Activators
The chemical class of SF3B2 Activators encompasses compounds that can indirectly influence the activity of SF3B2 through their effects on splicing factors, RNA processing, and related cellular signaling pathways. These compounds do not directly activate SF3B2; instead, they modulate cellular environments or pathways that could impact SF3B2's functional role in RNA splicing.
Compounds like Pladienolide B, Spliceostatin A, Meayamycin, Sudemycin D6, and E7107 target components of the spliceosome complex, potentially affecting SF3B2's activity in RNA splicing. Isoginkgetin and Herboxidiene, known for their inhibitory effects on mRNA splicing, represent potential indirect modulators of SF3B2. Histone deacetylase inhibitors like Trichostatin A and Vorinostat may affect gene expression patterns, potentially impacting the splicing activities of SF3B2. Proteasome inhibitors like Bortezomib and MG-132 could indirectly influence the dynamics of splicing factors, including SF3B2.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor, which can affect gene expression and potentially splicing processes involving SF3B2. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Another histone deacetylase inhibitor, potentially influencing RNA splicing activities of SF3B2. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
A proteasome inhibitor, could indirectly affect splicing factor dynamics and SF3B2's function. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
Another proteasome inhibitor, potentially impacting spliceosome components including SF3B2. | ||||||